It is well known that radiation therapy causes lymphopenia in patients and that this is
correlated with a negative outcome. The mechanism is not well understood because …

In the setting of conventional radiation therapy, even when combined with immunotherapy,
head and neck cancer often recurs locally and regionally. Elective nodal irradiation (ENI) is …

Radiation-induced lymphopenia (RIL) is characterized by a significant decrease in the
absolute number of lymphocytes circulating in the blood after radiotherapy. With the major …

There is a rising interest in developing and utilizing arc delivery techniques with charged
particle beams, eg, proton, carbon or other ions, for clinical implementation. In this work …

Introduction Durvalumab after concurrent chemoradiation (CCRT) for NSCLC improves
survival, but only in a subset of patients. We investigated the effect of severe radiation …

Purpose Lymphocytes play an important role in antitumor immunity; however, they are also
especially vulnerable to depletion during chemoradiation therapy (CRT). The purpose of this …

Simple Summary Radiotherapy is as an important part of esophageal cancer (EC) treatment.
However, it often causes severe radiation-induced lymphopenia (RIL). The aim of the current …

Objectives Radiotherapy is a key part of head and neck cancer (HNC) treatment. Radiation
induced lymphopenia (RIL) is a severe complication of radiotherapy. The aim of this study …

Background The nutritional status of cancer patients is a crucial factor in determining their
prognosis. The objective of this study was to investigate and compare the prognostic value …

Background The controlling nutritional status (CONUT) score, as an immune-nutritional
index, has been reported to be related to prognosis in several cancers. Neoadjuvant …