MRSA compendium of epidemiology, transmission, pathophysiology, treatment, and prevention within one health framework

M Shoaib, AI Aqib, I Muzammil, N Majeed… - Frontiers in …, 2023 - frontiersin.org
Staphylococcus aureus is recognized as commensal as well as opportunistic pathogen of
humans and animals. Methicillin resistant strain of S. aureus (MRSA) has emerged as a …

Biological activities and potential oral applications of N‐acetylcysteine: progress and prospects

Y Pei, H Liu, Y Yang, Y Yang, Y Jiao… - Oxidative medicine …, 2018 - Wiley Online Library
N‐Acetylcysteine (NAC), a cysteine prodrug and glutathione (GSH) precursor, has been
used for several decades in clinical therapeutic practices as a mucolytic agent and for the …

[HTML][HTML] The effect of N-acetylcysteine on biofilms: Implications for the treatment of respiratory tract infections

F Blasi, C Page, GM Rossolini, L Pallecchi… - Respiratory …, 2016 - Elsevier
Objectives In airway infections, biofilm formation has been demonstrated to be responsible
for both acute and chronic events, and constitutes a genuine challenge in clinical practice …

N-acetylcysteine (NAC) and Its Role in Clinical Practice Management of Cystic Fibrosis (CF): A Review

M Guerini, G Condrò, V Friuli, L Maggi, P Perugini - Pharmaceuticals, 2022 - mdpi.com
N-acetylcysteine is the acetylated form of the amino acid L-cysteine and a precursor to
glutathione (GSH). It has been known for a long time as a powerful antioxidant and as an …

Inhibition of Erythromycin and Erythromycin-Induced Resistance among Staphylococcus aureus Clinical Isolates

AA Mahfouz, HS Said, SM Elfeky, MI Shaaban - Antibiotics, 2023 - mdpi.com
The increasing incidence of erythromycin and erythromycin-induced resistance to
clindamycin among Staphylococcus aureus (S. aureus) is a serious problem. Patients …

[PDF][PDF] Molecular Characterization and Therapeutic Insights into Biofilm Positive Staphylococcus aureus Isolated from Bovine Subclinical Mastitis.

A Ahmed, M Ijaz, JA Khan, AA Anjum - Pakistan Veterinary Journal, 2022 - pvj.com.pk
The current study aimed to investigate the prevalence and molecular characterization of
biofilm-positive S. aureus isolates from bovine subclinical mastitis. The study also highlights …

NSAIDs as a drug repurposing strategy for biofilm control

C Leão, A Borges, M Simões - Antibiotics, 2020 - mdpi.com
Persistent infections, usually associated with biofilm-producing bacteria, are challenging for
both medical and scientific communities. The potential interest in drug repurposing for …

Crippling of Klebsiella pneumoniae virulence by metformin, N-acetylcysteine and secnidazole

S M. Shafik, HA Abbas, N Yousef, MM Saleh - BMC microbiology, 2023 - Springer
Introduction The emergence of multidrug-resistant Klebsiella pneumoniae in hospitals
represents a serious threat to public health. Infections caused by Klebsiella pneumoniae are …

Azithromycin possesses biofilm–inhibitory activity and potentiates non-bactericidal colistin methanesulfonate (CMS) and polymyxin B against Klebsiella pneumonia

OV Moshynets, TP Baranovskyi, S Cameron… - PLoS …, 2022 - journals.plos.org
Novel antibiotic combinations may act synergistically to inhibit the growth of multidrug-
resistant bacterial pathogens but predicting which combination will be successful is difficult …

Molecular evidence of β-lactam resistant Staphylococcus aureus in equids with respiratory tract infections: Frequency and resistance modulation strategy

H Rasheed, M Ijaz, I Muzammil, A Ahmed, F Anwaar… - Acta Tropica, 2023 - Elsevier
The emergence of antimicrobial-resistant strains in Staphylococcus aureus (β-lactam and
methicillin-resistant) is an overwhelming issue worldwide. Using the purposive sampling …