Versatile triad alliance: bile acid, taurine and microbiota

K Duszka - Cells, 2022 - mdpi.com
Taurine is the most abundant free amino acid in the body, and is mainly derived from the
diet, but can also be produced endogenously from cysteine. It plays multiple essential roles …

Role of the Microbiome in the Pathogenesis of COVID-19

R De, S Dutta - Frontiers in cellular and infection microbiology, 2022 - frontiersin.org
The ongoing pandemic coronavirus disease COVID-19 is caused by the highly contagious
single-stranded RNA virus, SARS-coronavirus 2 (SARS-CoV-2), which has a high rate of …

Clostridium butyricum potentially improves inflammation and immunity through alteration of the microbiota and metabolism of gastric cancer patients after gastrectomy

W Cao, C Zheng, X Xu, R Jin, F Huang, M Shi… - Frontiers in …, 2022 - frontiersin.org
Background Gastrectomy is the most effective treatment to improve the clinical survival rate
of patients with gastric cancer. However, the pathophysiological changes caused by …

Disruption of the intestinal mucosal barrier induced by high fructose and restraint stress is regulated by the intestinal microbiota and microbiota metabolites

J Yu, T Liu, Q Guo, Z Wang, Y Chen… - Microbiology …, 2023 - Am Soc Microbiol
Environmental (restraint stress) and dietary (high fructose) factors are key triggers for flares
of inflammatory bowel disease; however, the mechanisms involved in this phenomenon are …

Taurine alleviates cadmium-induced hepatotoxicity by regulating autophagy flux

Y Duan, Y Zhao, T Wang, J Sun, W Ali, Y Ma… - International Journal of …, 2023 - mdpi.com
Our previous studies have confirmed that cadmium (Cd) exposure causes hepatotoxicity; it
also induces autophagy and blocks the autophagy flux. Therefore, we hypothesized that Cd …

Enterogenic Stenotrophomonas maltophilia migrates to the mammary gland to induce mastitis by activating the calcium-ROS-AMPK-mTOR-autophagy pathway

Z He, C Zhao, Y He, Z Liu, G Fan, K Zhu… - Journal of Animal …, 2023 - Springer
Background Mastitis is an inflammatory disease of the mammary gland that has serious
economic impacts on the dairy industry and endangers food safety. Our previous study …

Taurine Reprograms Mammary-Gland Metabolism and Alleviates Inflammation Induced by Streptococcus uberis in Mice

R Lan, Z Wan, Y Xu, Z Wang, S Fu, Y Zhou… - Frontiers in …, 2021 - frontiersin.org
Streptococcus uberis (S. uberis) is an important pathogen causing mastitis, which causes
continuous inflammation and dysfunction of mammary glands and leads to enormous …

Sulforaphane prevents LPS-induced inflammation by regulating the Nrf2-mediated autophagy pathway in goat mammary epithelial cells and a mouse model of …

D Shao, W Shen, Y Miao, Z Gao, M Pan, Q Wei… - Journal of Animal …, 2023 - Springer
Background Mastitis not only deteriorates the composition or quality of milk, but also
damages the health and productivity of dairy goats. Sulforaphane (SFN) is a phytochemical …

Mycoplasma bovis inhibits autophagy in bovine mammary epithelial cells via a PTEN/PI3K-Akt-mTOR-dependent pathway

M Xu, Y Liu, T Mayinuer, Y Lin, Y Wang, J Gao… - Frontiers in …, 2022 - frontiersin.org
Although autophagy can eliminate some intracellular pathogens, others, eg, Staphylococcus
aureus, Salmonella, Mycoplasma bovis, can evade it. The phosphoinositide 3-kinase …

Integrated analysis of inflammatory mRNAs, miRNAs, and lncRNAs elucidates the molecular interactome behind bovine mastitis

A Hasankhani, M Bakherad, A Bahrami… - Scientific Reports, 2023 - nature.com
Mastitis is known as intramammary inflammation, which has a multifactorial complex
phenotype. However, the underlying molecular pathogenesis of mastitis remains poorly …