Molecular interactions between warfarin and human (HSA) or bovine (BSA) serum albumin evaluated by isothermal titration calorimetry (ITC), fluorescence …
C Ràfols, S Amézqueta, E Fuguet, E Bosch - Journal of Pharmaceutical …, 2018 - Elsevier
Interaction thermodynamics between warfarin, a very popular anticoagulant, and Sudlow I
binding site of human (HSA) or bovine (BSA) serum albumin have been examined in strictly …
binding site of human (HSA) or bovine (BSA) serum albumin have been examined in strictly …
Thermodynamics of the interaction of the food additive tartrazine with serum albumins: A microcalorimetric investigation
The thermodynamics of the interaction of the food colourant tartrazine with two homologous
serum proteins, HSA and BSA, were investigated, employing microcalorimetric techniques …
serum proteins, HSA and BSA, were investigated, employing microcalorimetric techniques …
Temperature induced morphological transitions from native to unfolded aggregated states of human serum albumin
The circulatory protein, human serum albumin (HSA), is known to have two melting point
temperatures, 56 and 62° C. In this present manuscript, we investigate the interaction of HSA …
temperatures, 56 and 62° C. In this present manuscript, we investigate the interaction of HSA …
Encapsulation of anticancer drug curcumin and co-loading with photosensitizer hypericin into lipoproteins investigated by fluorescence resonance energy transfer
A Jutkova, D Chorvat, P Miskovsky, D Jancura… - International journal of …, 2019 - Elsevier
Low-density lipoproteins (LDL) and high-density lipoproteins (HDL) are natural occurring
vehicles attractive for drug delivery and targeting tumor cells. Here we have investigated the …
vehicles attractive for drug delivery and targeting tumor cells. Here we have investigated the …
Detailed scrutiny of the anion receptor pocket in subdomain IIA of serum proteins toward individual response to specific ligands: HSA-pocket resembles flexible …
Present study reveals that the subdomain IIA cavity of two homologous serum albumins
(HSA, BSA) has inherent mutual structural and functional deviations which render noticeable …
(HSA, BSA) has inherent mutual structural and functional deviations which render noticeable …
Insights into the binding mechanism of BODIPY-based photosensitizers to human serum albumin: A combined experimental and computational study
Y Chen, J Liu, M Song, L Jiang, L Liu, Y Liu… - … Acta Part A: Molecular …, 2018 - Elsevier
Photodynamic therapy (PDT) is a noninvasive and effective approach in clinical cancer
treatments. Boron-dipyrromethene (BODIPY)-based derivatives have emerged as novel and …
treatments. Boron-dipyrromethene (BODIPY)-based derivatives have emerged as novel and …
Exploration of electrostatic interaction in the hydrophobic pocket of lysozyme: importance of ligand-induced perturbation of the secondary structure on the mode of …
Exogenous ligand binding can be adequate to alter the secondary structure of biomolecules
besides other external stimuli. In such cases, structural alterations can complicate on the …
besides other external stimuli. In such cases, structural alterations can complicate on the …
Ultrafast dynamics of a molecular rotor in chemical and biological nano-cavities
Molecular rotors have become indispensable tools in monitoring several important
processes in chemistry and biology owing to their sensitivity towards viscosity. Despite their …
processes in chemistry and biology owing to their sensitivity towards viscosity. Despite their …
Investigations of albumin–insulin Detemir complexes using molecular dynamics simulations and free energy calculations
LA Ryberg, P Sønderby, JT Bukrinski… - Molecular …, 2019 - ACS Publications
Insulin detemir is a lipidated insulin analogue that obtains a half-life extension by
oligomerization and reversible binding to human serum albumin. In the present study, the …
oligomerization and reversible binding to human serum albumin. In the present study, the …
Delineating the cascade of molecular events in protein aggregation triggered by Glyphosate, aminomethylphosphonic acid, and Roundup in serum albumins
The molecular basis of protein unfolding on exposure to the widely used herbicide,
Glyphosate (GLY), its metabolite aminomethylphosphonic acid (AMPA), and the commercial …
Glyphosate (GLY), its metabolite aminomethylphosphonic acid (AMPA), and the commercial …