Engineering biomaterials to tailor the microenvironment for macrophage–endothelium interactions
Macrophages and endothelial cells (ECs) have essential roles in physiological and
pathological conditions by regulating inflammation, vascularization and tissue remodelling …
pathological conditions by regulating inflammation, vascularization and tissue remodelling …
Perlecan, a multi-functional, cell-instructive, matrix-stabilizing proteoglycan with roles in tissue development has relevance to connective tissue repair and …
This review highlights the multifunctional properties of perlecan (HSPG2) and its potential
roles in repair biology. Perlecan is ubiquitous, occurring in vascular, cartilaginous, adipose …
roles in repair biology. Perlecan is ubiquitous, occurring in vascular, cartilaginous, adipose …
The role of the cell surface glycocalyx in drug delivery to and through the endothelium
Cell membranes are key interfaces where materials engineering meets biology. Traditionally
regarded as just the location of receptors regulating the uptake of molecules, we now know …
regarded as just the location of receptors regulating the uptake of molecules, we now know …
Smooth Muscle Cell—Macrophage Interactions Leading to Foam Cell Formation in Atherosclerosis: Location, Location, Location
Cholesterol-overloaded cells or “foam cells” in the artery wall are the biochemical hallmark
of atherosclerosis, and are responsible for much of the growth, inflammation and …
of atherosclerosis, and are responsible for much of the growth, inflammation and …
[HTML][HTML] Engineered short forms of perlecan enhance angiogenesis by potentiating growth factor signalling
Growth factors are key molecules involved in angiogenesis, a process critical for tissue
repair and regeneration. Despite the potential of growth factor delivery to stimulate …
repair and regeneration. Despite the potential of growth factor delivery to stimulate …
Extracellular matrix: paving the way to the newest trends in atherosclerosis
C Gialeli, A Shami, I Gonçalves - Current opinion in lipidology, 2021 - journals.lww.com
Extracellular matrix: paving the way to the newest trends in... : Current Opinion in Lipidology
Extracellular matrix: paving the way to the newest trends in atherosclerosis : Current Opinion …
Extracellular matrix: paving the way to the newest trends in atherosclerosis : Current Opinion …
Pentosan Polysulfate affords pleotropic protection to multiple cells and tissues
Pentosan polysulfate (PPS), a small semi-synthetic highly sulfated heparan sulfate (HS)-like
molecule, shares many of the interactive properties of HS. The aim of this review was to …
molecule, shares many of the interactive properties of HS. The aim of this review was to …
Unravelling the limb regeneration mechanisms of Polypedates maculatus, a sub-tropical frog, by transcriptomics
C Mahapatra, P Naik, SK Swain, PP Mohapatra - BMC genomics, 2023 - Springer
Background Regeneration studies help to understand the strategies that replace a lost or
damaged organ and provide insights into approaches followed in regenerative medicine …
damaged organ and provide insights into approaches followed in regenerative medicine …
Catalpol inhibits macrophage polarization and prevents postmenopausal atherosclerosis through regulating estrogen receptor alpha
Q Chen, X Qi, W Zhang, Y Zhang, Y Bi… - Frontiers in …, 2021 - frontiersin.org
Lacking estrogen increases the risk of atherosclerosis (AS) in postmenopausal women.
Inflammation plays a vital role in the pathological process of AS, and macrophages are …
Inflammation plays a vital role in the pathological process of AS, and macrophages are …
Status of biomarkers for the identification of stable or vulnerable plaques in atherosclerosis
V Lubrano, S Balzan - Clinical Science, 2021 - portlandpress.com
Atherosclerosis is a systemic inflammation of the arteries characterized by atherosclerotic
plaque due to the accumulation of lipids, inflammatory cells, apoptotic cells, calcium and …
plaque due to the accumulation of lipids, inflammatory cells, apoptotic cells, calcium and …