The implementation of next‐generation sequencing technologies has provided a sharp
picture of the genetic variability in the components and regulators of the alternative pathway …

Age‐related macular degeneration is a retinal disease that causes permanent loss of central
vision in people over the age of 65. Its pathogenesis may be related to mitochondrial …

Age-related macular degeneration (AMD) is a leading cause of blindness, and elucidating
its underlying disease mechanisms is vital to the development of appropriate therapeutics …

Rationale We hypothesized that the integration of multi-omics data sets can help unravel
some complex aspects of AMD pathophysiology. Our objectives were to identify correlation …

Abstract The targeted LC-MS/MS method has been widely applied for peptide quantification,
offering sensibility, specificity, and reproducibility to the analysis. However, it requires the …

More than 15 years ago, the results of the pivotal trials supporting the intravitreal use of
ranibizumab were published [1, 2]. The intravitreal application of anti-vascular endothelial …

Age-related macular degeneration (AMD) is a leading cause of blindness, and elucidating
its underlying disease mechanisms is vital to the development of appropriate therapeutics …

Age-related macular degeneration (AMD) is a frequent disorder of the central retina. So far,
the pathomechanisms of the disease are incompletely understood, precluding successful …