Cardioimmunology is a field that encompasses the immune cells and pathways that
modulate cardiac function in homeostasis and regulate the temporal balance between tissue …

The liver is a site of complex immune activity. The hepatic immune system tolerates
harmless immunogenic loads in homeostasis status, shelters liver function, while …

Background Pulmonary hypertension (PH) is a common complication of COPD, associated
with increased mortality and morbidity. Intriguingly, pulmonary vascular alterations have …

Background Multiple sclerosis (MS) is a neuroinflammatory demyelinating disease
characterized by motor deficits and cognitive decline. Many immune aspects of the disease …

Peripheral sensory neurons widely innervate various tissues to continuously monitor and
respond to environmental stimuli. Whether peripheral sensory neurons innervate the spleen …

Natural killer (NK) cells play an important role in recognizing and killing pathogen-infected
or malignant cells. Changes in their numbers or activation can contribute to several diseases …

Atherosclerosis is studied in models with dysfunctional lipid homeostasis—predominantly
the ApoE−/− mouse. The role of antigen-presenting cells (APCs) for lipid homeostasis is not …

Neurotropic viruses target the brain and contribute to neurologic diseases. C-type lectin
receptors (CLRs) are pattern recognition receptors that recognize carbohydrate structures …

A causal relationship exists among the aging process, organ decay and disfunction, and the
occurrence of various diseases including cancer. A genetically engineered mouse model …

Decade-long survival of plasma cells in the bone marrow has long been a puzzling matter.
To understand how plasma cells are maintained and supported by survival-niches to …