SARS-CoV-2 antiviral therapy
The development of effective antiviral therapy for COVID-19 is critical for those awaiting
vaccination, as well as for those who do not respond robustly to vaccination. This review …
vaccination, as well as for those who do not respond robustly to vaccination. This review …
Current insights into respiratory virus transmission and potential implications for infection control programs: a narrative review
Policies to prevent respiratory virus transmission in health care settings have traditionally
divided organisms into Droplet versus Airborne categories. Droplet organisms (for example …
divided organisms into Droplet versus Airborne categories. Droplet organisms (for example …
Divergent SARS-CoV-2 Omicron–reactive T and B cell responses in COVID-19 vaccine recipients
CH GeurtsvanKessel, D Geers, KS Schmitz… - Science …, 2022 - science.org
The severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) Omicron
variant is spreading rapidly, even in vaccinated individuals, raising concerns about immune …
variant is spreading rapidly, even in vaccinated individuals, raising concerns about immune …
Neutralization of SARS-CoV-2 Omicron by BNT162b2 mRNA vaccine–elicited human sera
A Muik, BG Lui, AK Wallisch, M Bacher, J Mühl… - Science, 2022 - science.org
The globally circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variant of concern Omicron (B. 1.1. 529) has a large number of mutations, especially in the …
variant of concern Omicron (B. 1.1. 529) has a large number of mutations, especially in the …
Omicron BA. 1 breakthrough infection drives cross-variant neutralization and memory B cell formation against conserved epitopes
J Quandt, A Muik, N Salisch, BG Lui, S Lutz… - Science …, 2022 - science.org
Omicron is the evolutionarily most distinct severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) variant of concern (VOC) to date. We report that Omicron BA. 1 breakthrough …
(SARS-CoV-2) variant of concern (VOC) to date. We report that Omicron BA. 1 breakthrough …
Rapid assessment of SARS-CoV-2–evolved variants using virus-like particles
Efforts to determine why new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) variants demonstrate improved fitness have been limited to analyzing mutations in the …
2) variants demonstrate improved fitness have been limited to analyzing mutations in the …
Heterologous infection and vaccination shapes immunity against SARS-CoV-2 variants
CJ Reynolds, JM Gibbons, C Pade, KM Lin… - Science, 2022 - science.org
The impact of the initial severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infecting strain on downstream immunity to heterologous variants of concern (VOCs) is …
infecting strain on downstream immunity to heterologous variants of concern (VOCs) is …
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection
Broadly neutralizing antibodies (bnAbs) to coronaviruses (CoVs) are valuable in their own
right as prophylactic and therapeutic reagents to treat diverse CoVs and as templates for …
right as prophylactic and therapeutic reagents to treat diverse CoVs and as templates for …
S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters
M Sasaki, K Tabata, M Kishimoto, Y Itakura… - Science translational …, 2022 - science.org
In parallel with vaccination, oral antiviral agents are highly anticipated to act as
countermeasures for the treatment of the coronavirus disease 2019 (COVID-19) pandemic …
countermeasures for the treatment of the coronavirus disease 2019 (COVID-19) pandemic …
Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain
KG Nabel, SA Clark, S Shankar, J Pan, LE Clark… - Science, 2021 - science.org
Many studies have examined the impact of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) variants on neutralizing antibody activity after they have become dominant …
(SARS-CoV-2) variants on neutralizing antibody activity after they have become dominant …