[HTML][HTML] Pancreatic cancer in 2021: What you need to know to win

V Tonini, M Zanni - World Journal of Gastroenterology, 2021 - ncbi.nlm.nih.gov
Pancreatic cancer is one of the solid tumors with the worst prognosis. Five-year survival rate
is less than 10%. Surgical resection is the only potentially curative treatment, but the tumor is …

[HTML][HTML] EMT, CTCs and CSCs in tumor relapse and drug-resistance

A Mitra, L Mishra, S Li - Oncotarget, 2015 - ncbi.nlm.nih.gov
Tumor relapse and metastasis are the primary causes of poor survival rates in patients with
advanced cancer despite successful resection or chemotherapeutic treatment. A primary …

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

AV Biankin, N Waddell, KS Kassahn, MC Gingras… - Nature, 2012 - nature.com
Pancreatic cancer is a highly lethal malignancy with few effective therapies. We performed
exome sequencing and copy number analysis to define genomic aberrations in a …

Borderline resectable pancreatic cancer: a consensus statement by the International Study Group of Pancreatic Surgery (ISGPS)

M Bockhorn, FG Uzunoglu, M Adham, C Imrie… - Surgery, 2014 - Elsevier
Background This position statement was developed to expedite a consensus on definition
and treatment for borderline resectable pancreatic ductal adenocarcinoma (BRPC) that …

Pancreatic cancer surgery: the new R-status counts

O Strobel, T Hank, U Hinz, F Bergmann… - Annals of …, 2017 - journals.lww.com
Objective: To assess the relevance of resection margin status for survival outcome after
resection and adjuvant therapy for pancreatic cancer. Background: The definitions for R0 …

[HTML][HTML] Pathology of pancreatic cancer

L Haeberle, I Esposito - Translational gastroenterology and …, 2019 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy and
estimated to become the second leading cause of cancer-related deaths by 2030. Although …

Impact of resection margin status on recurrence and survival in pancreatic cancer surgery

WS Tummers, JV Groen… - Journal of British …, 2019 - academic.oup.com
Background The prognosis of patients with pancreatic ductal adenocarcinoma (PDAC) is
poor and selection of patients for surgery is challenging. This study examined the impact of a …

The impact of positive resection margins on survival and recurrence following resection and adjuvant chemotherapy for pancreatic ductal adenocarcinoma

P Ghaneh, J Kleeff, CM Halloran, M Raraty… - Annals of …, 2019 - journals.lww.com
Methods: Analyses were carried out to assess the association between clinical
characteristics and margin involvement as well as the effects of individual margin …

Pancreatic ductal adenocarcinoma: is there a survival difference for R1 resections versus locally advanced unresectable tumors? What is a “true” R0 resection?

IT Konstantinidis, AL Warshaw, JN Allen… - Annals of …, 2013 - journals.lww.com
Objective: Patients who undergo an R0 resection of their pancreatic ductal adenocarcinoma
(PDAC) have an improved survival compared with patients who undergo an R1 resection. It …

R0 versus R1 resection matters after pancreaticoduodenectomy, and less after distal or total pancreatectomy for pancreatic cancer

IE Demir, C Jäger, AM Schlitter, B Konukiewitz… - Annals of …, 2018 - journals.lww.com
Objective: The aim of this study was to decipher the true importance of R0 versus R1
resection for survival in pancreatic ductal adenocarcinoma (PDAC). Summary of …