Recent advances in exosome-mediated nucleic acid delivery for cancer therapy

Y Zhang, Q Liu, X Zhang, H Huang, S Tang… - Journal of …, 2022 - Springer
Cancer is a leading public health problem worldwide. Its treatment remains a daunting
challenge, although significant progress has been made in existing treatments in recent …

Current strategies for exosome cargo loading and targeting delivery

H Zeng, S Guo, X Ren, Z Wu, S Liu, X Yao - Cells, 2023 - mdpi.com
Extracellular vesicles (EVs) such as ectosomes and exosomes have gained attention as
promising natural carriers for drug delivery. Exosomes, which range from 30 to 100 nm in …

Understanding the roles and regulation patterns of circRNA on its host gene in tumorigenesis and tumor progression

J Wei, M Li, C Xue, S Chen, L Zheng, H Deng… - Journal of Experimental …, 2023 - Springer
Circular RNAs (circRNAs) are a novel type of endogenous non-coding RNAs, which are
covalently closed loop structures formed by precursor mRNAs (pre-mRNAs) through back …

CircRNAs in colorectal cancer: potential biomarkers and therapeutic targets

Y Zhang, J Luo, W Yang, WC Ye - Cell death & disease, 2023 - nature.com
Globally, colorectal cancer (CRC) is the third most prevalent cancer and the second leading
cause of cancer-related deaths. Circular RNAs (circRNAs) are single-stranded RNA with …

Circular RNA cFAM210A, degradable by HBx, inhibits HCC tumorigenesis by suppressing YBX1 transactivation

J Yu, W Li, G Hou, D Sun, Y Yang, S Yuan… - … & Molecular Medicine, 2023 - nature.com
Hepatitis B protein x (HBx) has been reported to promote tumorigenesis in hepatitis B virus
(HBV)-related hepatocellular carcinoma (HCC), but the mechanism awaits further …

Recent advances of exosomal circRNAs in cancer and their potential clinical applications

Q Yi, J Yue, Y Liu, H Shi, W Sun, J Feng… - Journal of translational …, 2023 - Springer
Circular RNA (circRNA) is a type of non-coding RNA that forms a covalently closed,
uninterrupted loop. The expression of circRNA differs among cell types and tissues, and …

Exosomal circRNAs in cancer: implications for therapy resistance and biomarkers

Z Lin, Y Ji, J Zhou, G Li, Y Wu, W Liu, Z Li, T Liu - Cancer Letters, 2023 - Elsevier
Despite the advances in cancer treatment in recent years, the development of resistance to
cancer therapy remains the biggest hurdle towards curative cancer treatments. Therefore …

Extracellular vesicles in colorectal cancer: from tumor growth and metastasis to biomarkers and nanomedications

L Kotelevets, E Chastre - Cancers, 2023 - mdpi.com
Simple Summary Almost all cell types produce extracellular vesicles that, according to their
size, subcellular origin and release pathways, are mainly categorized as exosomes …

LncRNA BCCE4 Genetically Enhances the PD‐L1/PD‐1 Interaction in Smoking‐Related Bladder Cancer by Modulating miR‐328‐3p‐USP18 Signaling

R Zheng, F Gao, Z Mao, Y Xiao, L Yuan… - Advanced …, 2023 - Wiley Online Library
Identification of cancer‐associated variants, especially those in functional regions of long
noncoding RNAs (lncRNAs), has become an essential task in tumor etiology. However, the …

Roles of exosomal circRNAs in tumour immunity and cancer progression

B Tuo, Z Chen, Q Dang, C Chen, H Zhang, S Hu… - Cell Death & …, 2022 - nature.com
Tumour immunity plays an important role in the development of cancer. Tumour
immunotherapy is an important component of antitumour therapy. Exosomes, a type of …