Density estimation of SARS-CoV2 spike proteins using super pixels segmentation technique

BA Taha, Q Al-Jubouri, Y Al Mashhadany… - Applied soft …, 2023 - Elsevier
The worldwide outbreak of COVID-19 disease was caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV 2). The existence of spike proteins, which allow these …

Progress of proteomics‐driven precision medicine: From a glycosylation view

Y Liang, B Fu, Y Zhang, H Lu - Rapid Communications in Mass …, 2022 - Wiley Online Library
Currently, cancer is one of the leading causes of death worldwide, partially owing to the lack
of early diagnosis methods and effective therapies. With the rapid development of various …

Enabling neighbour labelling: using synthetic biology to explore how cells influence their neighbours

M Malaguti, T Lebek, G Blin, S Lowell - Development, 2024 - journals.biologists.com
Cell-cell interactions are central to development, but exploring how a change in any given
cell relates to changes in the neighbour of that cell can be technically challenging. Here, we …

Small extracellular vesicles convey the stress-induced adaptive responses of melanoma cells

M Harmati, E Gyukity-Sebestyen, G Dobra, L Janovak… - Scientific reports, 2019 - nature.com
Exosomes are small extracellular vesicles (sEVs), playing a crucial role in the intercellular
communication in physiological as well as pathological processes. Here, we aimed to study …

[PDF][PDF] SyNPL: Synthetic Notch pluripotent cell lines to monitor and manipulate cell interactions in vitro and in vivo

M Malaguti, R Portero Migueles, J Annoh… - …, 2022 - journals.biologists.com
Cell-cell interactions govern differentiation and cell competition in pluripotent cells during
early development, but the investigation of such processes is hindered by a lack of efficient …

Machine learning analysis for quantitative discrimination of dried blood droplets

L Hamadeh, S Imran, M Bencsik, GR Sharpe… - Scientific reports, 2020 - nature.com
One of the most interesting and everyday natural phenomenon is the formation of different
patterns after the evaporation of liquid droplets on a solid surface. The analysis of dried …

AI-driven Deep Visual Proteomics defines cell identity and heterogeneity

A Mund, F Coscia, R Hollandi, F Kovács, A Kriston… - BioRxiv, 2021 - biorxiv.org
The systems-wide analysis of biomolecules in time and space is key to our understanding of
cellular function and heterogeneity in health and disease. Remarkable technological …

Nessys: A new set of tools for the automated detection of nuclei within intact tissues and dense 3D cultures

G Blin, D Sadurska, R Portero Migueles, N Chen… - PLoS …, 2019 - journals.plos.org
Methods for measuring the properties of individual cells within their native 3D environment
will enable a deeper understanding of embryonic development, tissue regeneration, and …

Fisheye transformation enhances deep-learning-based single-cell phenotyping by including cellular microenvironment

T Toth, D Bauer, F Sukosd, P Horvath - Cell Reports Methods, 2022 - cell.com
Incorporating information about the surroundings can have a significant impact on
successfully determining the class of an object. This is of particular interest when …

Image processing filters for grids of cells analogous to filters processing grids of pixels

R Haase - Frontiers in Computer Science, 2021 - frontiersin.org
Intra-and extra-cellular processes shape tissues together. For understanding how
neighborhood relationships between cells play a role in this process, having image …