The last few decades have witnessed unprecedented convergence between humans and
machines that closely operate around the human body. Despite these advances, traditional …

Hydrogels from biopolymers are readily synthesized, can possess various characteristics for
different applications, and have been widely used in biomedicine to help with patient …

Graft-host mechanical mismatch has been a longstanding issue in clinical applications of
synthetic scaffolds for soft tissue regeneration. Although numerous efforts have been …

A variety of soft, hydrogel-like materials with sophisticated micro-and nanoengineered
ordered structures that offer excellent functionalities exist in nature. Conventional synthetic …

Gradient scaffolds are isotropic/anisotropic three-dimensional structures with gradual
transitions in geometry, density, porosity, stiffness, etc., that mimic the biological extracellular …

Tendon injuries disrupt the balance between stability and mobility, causing compromised
functions and disabilities. The regeneration of mature, functional tendons remains a clinical …

Engineering synthetic scaffolds to repair and regenerate ruptured native tendon and
ligament (T/L) tissues is a significant engineering challenge due to the need to satisfy both …

Decellularized tissues are a valid alternative as tissue engineering scaffolds, thanks to the
three-dimensional structure that mimics native tissues to be regenerated and the biomimetic …

Appropriate macrophage response to an implanted biomaterial is crucial for successful
tissue healing outcomes. In this work we investigated how intrinsic topological cues from …

The key attributes of core–shell fibers are their ability to preserve bioactivity of incorporated-
sensitive biomolecules (such as drug, protein, and growth factor) and subsequently control …