A systematic review and meta-analysis to determine the effect of sperm DNA damage on in vitro fertilization and intracytoplasmic sperm injection outcome
L Simon, A Zini, A Dyachenko, A Ciampi… - Asian journal of …, 2017 - journals.lww.com
Sperm DNA damage is prevalent among infertile men and is known to influence natural
reproduction. However, the impact of sperm DNA damage on assisted reproduction …
reproduction. However, the impact of sperm DNA damage on assisted reproduction …
Measuring sperm DNA fragmentation and clinical outcomes of medically assisted reproduction: a systematic review and meta-analysis
M Cissen, M Wely, I Scholten, S Mansell, JP Bruin… - PloS one, 2016 - journals.plos.org
Sperm DNA fragmentation has been associated with reduced fertilization rates, embryo
quality, pregnancy rates and increased miscarriage rates. Various methods exist to test …
quality, pregnancy rates and increased miscarriage rates. Various methods exist to test …
[HTML][HTML] Do sperm DNA integrity tests predict pregnancy with in vitro fertilization?
JA Collins, KT Barnhart, PN Schlegel - Fertility and sterility, 2008 - Elsevier
OBJECTIVE: To evaluate the predictive value of sperm DNA integrity tests for pregnancy
from in vitro fertilization treatment. DESIGN: Systematic review and meta-analysis. SETTING …
from in vitro fertilization treatment. DESIGN: Systematic review and meta-analysis. SETTING …
[HTML][HTML] Extent of nuclear DNA damage in ejaculated spermatozoa impacts on blastocyst development after in vitro fertilization
E Seli, DK Gardner, WB Schoolcraft, O Moffatt… - Fertility and sterility, 2004 - Elsevier
OBJECTIVE: To determine whether the extent of ongoing apoptotic cell death measured as
the presence of DNA strand breaks in spermatozoa affects embryo development to the …
the presence of DNA strand breaks in spermatozoa affects embryo development to the …
Are sperm chromatin and DNA defects relevant in the clinic?
A Zini - Systems biology in reproductive medicine, 2011 - Taylor & Francis
There has been an increase in the use of sperm DNA and chromatin integrity tests in the
evaluation of the infertile man with the hypothesis that these tests may better diagnose …
evaluation of the infertile man with the hypothesis that these tests may better diagnose …
Are tests of sperm DNA damage clinically useful? Pros and cons
A Zini, M Sigman - Journal of andrology, 2009 - Wiley Online Library
The advent of assisted reproductive technologies, particularly intracytoplasmic sperm
injection (ICSI), has revolutionized the treatment of male‐factor infertility. However, there are …
injection (ICSI), has revolutionized the treatment of male‐factor infertility. However, there are …
Comparison of chromatin assays for DNA fragmentation evaluation in human sperm
KR Chohan, JT Griffin, M Lafromboise… - Journal of …, 2006 - Wiley Online Library
Sperm chromatin integrity is vital for successful pregnancy and transmission of genetic
material to the offspring. We evaluated chromatin integrity in sperm from 60 infertile men and …
material to the offspring. We evaluated chromatin integrity in sperm from 60 infertile men and …
Full‐term pregnancies achieved with ICSI despite high levels of sperm chromatin damage
L Gandini, F Lombardo, D Paoli, F Caruso… - Human …, 2004 - academic.oup.com
BACKGROUND: Sperm DNA integrity is essential for the accurate transmission of genetic
information. The clinical significance of this assessment lies in its association with not only …
information. The clinical significance of this assessment lies in its association with not only …
DNA integrity is compromised in protamine‐deficient human sperm
VW Aoki, SI Moskovtsev, J Willis, L Liu… - Journal of …, 2005 - Wiley Online Library
The objective of this study was to examine the relationship between DNA integrity and
protamines in human sperm. One hundred forty‐nine male infertility patients were included …
protamines in human sperm. One hundred forty‐nine male infertility patients were included …
[HTML][HTML] Sperm DNA fragmentation negatively correlates with velocity and fertilization rates but might not affect pregnancy rates
CC Huang, DPC Lin, HM Tsao, TC Cheng, CH Liu… - Fertility and sterility, 2005 - Elsevier
OBJECTIVE: To evaluate sperm DNA fragmentation in correlation with sperm parameters
and IVF/intracytoplasmic sperm injection (ICSI) outcomes. DESIGN: Retrospective review …
and IVF/intracytoplasmic sperm injection (ICSI) outcomes. DESIGN: Retrospective review …