Recombinant proteins are the most important product of current industrial biotechnology.
They are indispensable in medicine (for diagnostics and treatment), food and chemical …

To introduce DNA into mitochondria efficiently, we fused adenoassociated virus capsid VP2
with a mitochondrial targeting sequence to carry the mitochondrial gene encoding the …

Many mitochondrial genes have been transferred to the nucleus in course of evolution. The
products of expression of these genes, being still necessary for organelle function, are …

Gene delivery targeting mitochondria has the potential to transform the therapeutic
landscape of mitochondrial genetic diseases. Taking advantage of the nonuniversal genetic …

The design and synthesis of multifunctional nanomaterials could lead to applications
relevant for biomedicine. Manufacturing porous particles to make them able to carry …

Mitochondria possess transport mechanisms for import of RNA and DNA. Based on import
into isolated Solanum tuberosum mitochondria in the presence of competitors, inhibitors or …

Mitochondria have retained indispensable but limited genetic information and they import
both proteins and nucleic acids from the cytosol. RNA import is essential for gene …

In plants, the voltage-dependent anion-selective channel (VDAC) is a major component of a
pathway involved in transfer RNA (tRNA) translocation through the mitochondrial outer …

Mitochondria have their own gene expression system that is independent of the nuclear
system, and control cellular functions in cooperation with the nucleus. While a number of …

Given the essential functions of these organelles in cell homeostasis, their involvement in
incurable diseases and their potential in biotechnological applications, genetic …