Impact of thrombophilia on risk of arterial ischemic stroke or cerebral sinovenous thrombosis in neonates and children: a systematic review and meta-analysis of …

G Kenet, LK Lütkhoff, M Albisetti, T Bernard… - Circulation, 2010 - Am Heart Assoc
Background—The aim of this study was to estimate the impact of thrombophilia on risk of first
childhood stroke through a meta-analysis of published observational studies. Methods and …

Pediatric arterial ischemic stroke: Epidemiology, risk factors, and management

RJ Felling, LR Sun, EC Maxwell, N Goldenberg… - Blood Cells, Molecules …, 2017 - Elsevier
Pediatric arterial ischemic stroke (AIS) is an uncommon but important cause of neurologic
morbidity in neonates and children, with consequences including hemiparesis, intellectual …

Factor V Leiden and antiphospholipid antibodies in either mothers or infants increase the risk for perinatal arterial ischemic stroke

MJ Simchen, G Goldstein, A Lubetsky, T Strauss… - Stroke, 2009 - Am Heart Assoc
Background and Purpose—The objective was to investigate the role of infant and maternal
thrombophilia in a cohort of mothers and infants presenting with perinatal arterial ischemic …

[HTML][HTML] Factor V Leiden thrombophilia

JL Kujovich - 2018 - europepmc.org
Factor V Leiden thrombophilia is characterized by a poor anticoagulant response to
activated protein C (APC) and an increased risk for venous thromboembolism (VTE). Deep …

Epidemiology of the antiphospholipid syndrome

L Durcan, M Petri - Handbook of systemic autoimmune diseases, 2017 - Elsevier
Antiphospholipid antibodies (aPL) are implicated in approximately a quarter of a million
thrombotic events in the United States annually. These antibodies, anticardiolipin, anti-β2 …

Role of investigating thrombophilic disorders in young stroke

KWP Ng, PK Loh, VK Sharma - Stroke research and treatment, 2011 - Wiley Online Library
Our knowledge about various inherited and acquired causes of thrombophilic disorders has
increased significantly during the past decade. Technology for various diagnostic tests for …

Inherited prothrombotic risk factors in children with first ischemic stroke

R Zadro, D Coen Herak - Biochemia Medica, 2012 - hrcak.srce.hr
Sažetak Stroke in children is a heterogeneous disorder. Over 100 risk factors for stroke have
been reported and genetic predisposition to stroke has been established. The most …

Impact of persistent antiphospholipid antibodies on risk of incident symptomatic thromboembolism in children: a systematic review and meta-analysis

G Kenet, S Aronis, Y Berkun, M Bonduel… - … in thrombosis and …, 2011 - thieme-connect.com
The aim of this study was to estimate the impact of antiphospholipid (aPL) antibodies on the
risk of incident thromboembolism (TE; arterial and venous) in children via meta-analysis of …

[HTML][HTML] Systematic review: hereditary thrombophilia associated to pediatric strokes and cerebral palsy

VM Torres, VA Saddi - Jornal de pediatria, 2015 - SciELO Brasil
OBJECTIVES: This review aimed to organize and consolidate the latest knowledge about
mutations and genetic polymorphisms related to hereditary thrombophilia and their potential …

Factoring in factor VIII with acute ischemic stroke

JE Siegler, A Samai, KC Albright… - Clinical and Applied …, 2015 - journals.sagepub.com
There is growing research interest into the etiologies of cryptogenic stroke, in particular as it
relates to hypercoagulable states. An elevation in serum levels of the procoagulant factor VIII …