The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …

The endocannabinoid system (ECS) is one of the most crucial systems in the human
organism, exhibiting multi-purpose regulatory character. It is engaged in a vast array of …

Sex-dependent differences are frequently observed in the biological and behavioural effects
of substances of abuse, including cannabis. We recently demonstrated a modulating effect …

Oxytocin is a potent inducer of penile erection when injected into the central nervous system.
In male rats, the most sensitive brain area for the pro-erectile effect of oxytocin is the …

Male sexual behavior comprises a complex pattern of genital and somatomotor responses,
elicited, directed, and maintained by external and internal signals. It includes copulation as …

A continuously increasing amount of research shows that oxytocin is involved in numerous
central functions. Among the functions in which oxytocin is thought to be involved are those …

The putative role of the endocannabinoid system and the effects of cannabis use in male
and female sexual functioning are summarized. The influence of cannabis intake on sexual …

Rewarding behaviours such as sexual activity, eating, nursing, parenting, social interactions,
and play activity are conserved strongly in evolution, and they are essential for development …

Introduction Cannabis (marijuana) is the most widely used illicit drug globally. Given the
prevalence of nonprescription illicit drug abuse, there is a growing interest in the study of its …

G protein-coupled receptors (GPCRs) are the largest family of transmembrane receptors in
the mammalian genome. They are activated by a multitude of different ligands that elicit …