Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable
membrane environment for proteins to being embedded in to detailed roles in complicated …

The scientific study of protein surfactant interactions goes back more than a century, and has
been put to practical uses in everything from the estimation of protein molecular weights to …

A major obstacle in the study of membrane proteins is their solubilization in a stable and
active conformation when using detergents. Here, we explored a detergent-free approach to …

Ion channel conformational changes within the lipid membrane are a key requirement to
control ion passage. Thus, it seems reasonable to assume that lipid composition should …

Oomycetes such as Phytophthora sojae employ effector proteins that enter plant cells to
facilitate infection. Entry of some effector proteins is mediated by RxLR motifs in the effectors …

Research on ion channel modulation has become a hot topic because of the key roles these
membrane proteins play in both prokaryotic and eukaryotic organisms. In this respect, lipid …

The role of arginines R64 and R89 at non-annular lipid binding sites of KcsA, on the
modulation of channel activity by anionic lipids has been investigated. In wild-type (WT) …

KcsA, a prokaryote tetrameric potassium channel, was the first ion channel ever to be
structurally solved at high resolution. This, along with the ease of its expression and …

The most essential properties of ion channels for their physiologically relevant functions are
ion‐selective permeation and gating. Among the channel species, the potassium channel is …

While interactions of single-span transmembrane helices have been studied to a significant
extent in the past years, the folding of polytopic α-helical transmembrane proteins, as well as …