Mitochondrial dysfunction in PCOS: insights into Reproductive Organ Pathophysiology

KM Siemers, AK Klein, ML Baack - International Journal of Molecular …, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) is a complex, but relatively common endocrine disorder
associated with chronic anovulation, hyperandrogenism, and micro-polycystic ovaries. In …

Molecular mechanisms of the therapeutic effect of selenium nanoparticles in hepatocellular carcinoma

EG Varlamova - Cells, 2024 - mdpi.com
This review describes and summarizes, for the first time, the molecular mechanisms of the
cytotoxic effect of selenium nanoparticles of various origins on hepatocellular carcinoma …

[HTML][HTML] A five-in-one novel MOF-modified injectable hydrogel with thermo-sensitive and adhesive properties for promoting alveolar bone repair in periodontitis …

S Yang, Y Zhu, C Ji, H Zhu, A Lao, R Zhao, Y Hu… - Bioactive materials, 2024 - Elsevier
Periodontitis is a chronic inflammatory disease caused by plaque that destroys the alveolar
bone tissues, resulting in tooth loss. Poor eradication of pathogenic microorganisms …

Systematic low-grade chronic inflammation and intrinsic mechanisms in polycystic ovary syndrome

H Deng, Y Chen, J Xing, N Zhang, L Xu - Frontiers in Immunology, 2024 - frontiersin.org
Polycystic ovary syndrome (PCOS) is a prevalent endocrine and metabolic disorder affecting
6-20% of women of childbearing age worldwide. Immune cell imbalance and dysregulation …

Androgen excess: a hallmark of polycystic ovary syndrome

K Wang, Y Li, Y Chen - Frontiers in Endocrinology, 2023 - frontiersin.org
Polycystic ovarian syndrome (PCOS) is a metabolic, reproductive, and psychological
disorder affecting 6–20% of reproductive women worldwide. However, there is still no cure …

Polycystic ovary syndrome and related inflammation in radiomics; relationship with patient outcome

CY Zheng, YX Yu, X Bai - Seminars in Cell & Developmental Biology, 2024 - Elsevier
Polycystic ovary syndrome (PCOS) refers to a condition that often has 'poly'liquid containing
sacks around ovaries. It affects reproductive-aged females giving rise to menstrual and …

The utilization of nanotechnology in the female reproductive system and related disorders

X Luo, K Jia, J Xing, J Yi - Heliyon, 2024 - cell.com
The health of the reproductive system is intricately linked to female fertility and quality of life.
There has been a growing prevalence of reproductive system disorders among women …

[HTML][HTML] Potential role of molecular hydrogen therapy on oxidative stress and redox signaling in chronic kidney disease

CM Zheng, YC Hou, MT Liao, KW Tsai, WC Hu… - Biomedicine & …, 2024 - Elsevier
Oxidative stress plays a key role in chronic kidney disease (CKD) development and
progression, inducing kidney cell damage, inflammation, and fibrosis. However, effective …

Nanoparticle-Based Interventions for Polycystic Ovary Syndrome: A Review of Mechanisms and Therapeutic Potential

D Muthukumaran, R Shanmugam - Journal of Drug Delivery Science and …, 2024 - Elsevier
Polycystic Ovarian Syndrome (PCOS) affects many women of reproductive age and is
marked by hormonal imbalances, insulin resistance, chronic inflammation, and oxidative …

White-brown adipose tissue interplay in polycystic ovary syndrome: Therapeutic avenues

K Abbasi, R Zarezadeh, A Valizadeh… - Biochemical …, 2024 - Elsevier
This study highlights the therapeutic potential of activating brown adipose tissue (BAT) for
managing polycystic ovary syndrome (PCOS), a prevalent endocrine disorder associated …