Ultrasound‐mediated nano‐sized drug delivery systems for cancer treatment: Multi‐scale and multi‐physics computational modeling

F Moradi Kashkooli, TK Hornsby… - Wiley …, 2024 - Wiley Online Library
Computational modeling enables researchers to study and understand various complex
biological phenomena in anticancer drug delivery systems (DDSs), especially nano‐sized …

Metal-based nanoparticle in cancer treatment: lessons learned and challenges

A Hheidari, J Mohammadi, M Ghodousi… - … in Bioengineering and …, 2024 - frontiersin.org
Cancer, being one of the deadliest diseases, poses significant challenges despite the
existence of traditional treatment approaches. This has led to a growing demand for …

Microneedle patch capable of dual drug release for drug delivery to brain tumors

R Mousavi, M Soltani, M Souri - Drug Delivery and Translational Research, 2024 - Springer
Primary brain tumors are mostly managed using surgical resection procedures.
Nevertheless, in certain cases, a thin layer of tumors may remain outside of the resection …

A comparative study between conventional chemotherapy and photothermal activated nano-sized targeted drug delivery to solid tumor

MK Shahvandi, M Souri, S Tavasoli… - Computers in Biology …, 2023 - Elsevier
Delivery of chemotherapeutic medicines to solid tumors is critical for optimal therapeutic
success and minimal adverse effects. We mathematically developed a delivery method …

Kinetic modelling of ultrasound-triggered chemotherapeutic drug release from the surface of gold nanoparticles

TK Hornsby, FM Kashkooli, A Jakhmola, MC Kolios… - Scientific Reports, 2023 - nature.com
Therapeutic ultrasound can be used to trigger the on-demand release of chemotherapeutic
drugs from gold nanoparticles (GNPs). In the previous work, our group achieved doxorubicin …

A comprehensive review of lessons learned from quantum dots in cancer therapy

J Mohammadi, A Hheidari, S Sardari, M Nouri… - Biomedical …, 2024 - iopscience.iop.org
Quantum dots (QDs) are with exceptional physicochemical and biological properties,
making them highly versatile for a wide range of applications in cancer therapy. One of the …

Improving tumor treatment through intratumoral injection of drug-loaded magnetic nanoparticles and low-intensity ultrasound

A Hosseinpour, M Soltani, M Souri - Scientific Reports, 2024 - nature.com
The intratumoral injection of therapeutic agents responsive to external stimuli has gained
considerable interest in treating accessible tumors due to its biocompatibility and capacity to …

Enhancing localized chemotherapy with anti-angiogenesis and nanomedicine synergy for improved tumor penetration in well-vascularized tumors

M Souri, S Elahi, F Moradi Kashkooli… - npj Systems Biology …, 2024 - nature.com
Intratumoral delivery and localized chemotherapy have demonstrated promise in tumor
treatment; however, the rapid drainage of therapeutic agents from well-vascularized tumors …

[HTML][HTML] Localized radiotherapy of solid tumors using radiopharmaceutical loaded implantable system: insights from a mathematical model

A Piranfar, M Souri, A Rahmim, M Soltani - Frontiers in Oncology, 2024 - frontiersin.org
Introduction Computational models yield valuable insights into biological interactions not
fully elucidated by experimental approaches. This study investigates an innovative …

Genetic-bioengineering of nanotechnology in cell-specific pharmaceutical targeting: Biological, pharmacological, and biochemical impact of nanomaterials-based …

J Mohammadi, S Ebrahimi, M Ghodousi… - Journal of Drug Delivery …, 2024 - Elsevier
Addressing breast cancer is an ongoing global health concern, demanding constant
progress in treatment approaches due to its high incidence and mortality rates. In recent …