The risk of Alzheimer disease (AD) increases with age, family history and informative genetic
variants. Sadly, there is still no cure or means of prevention. As in other complex diseases …

Alzheimer's disease (AD) is an age-related neurodegenerative disease with multiple
predisposing factors and complicated pathogenesis. Aβ peptide is one of the most important …

Importance Compared with non-Hispanic White individuals, African American individuals
from the same community are approximately twice as likely to develop Alzheimer disease …

Autoimmunity and autoinflammation arise from aberrant immunological and inflammatory
responses toward self-components, contributing to various autoimmune diseases and …

Abstract Introduction The Alzheimer's Disease Neuroimaging Initiative (ADNI) has
accumulated 15 years of clinical, neuroimaging, cognitive, biofluid biomarker and genetic …

Abstract The Worldwide Alzheimer's Disease Neuroimaging Initiative (WW‐ADNI) is a
collaborative effort to investigate imaging and biofluid markers that can inform Alzheimer's …

Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disease. Due to
its long clinical course and lack of an effective treatment, AD has become a major public …

Approximately 30% of older adults exhibit the neuropathological features of Alzheimer's
disease without signs of cognitive impairment. Yet, little is known about the genetic factors …

Objective To examine whether amyloid PET in cognitively normal (CN) individuals screened
for the Anti-Amyloid in Asymptomatic Alzheimer's Disease (A4) study differed across self …

Approximately 30% of elderly adults are cognitively unimpaired at time of death despite the
presence of Alzheimer's disease neuropathology at autopsy. Studying individuals who are …