Acute Liver Failure | New England Journal of Medicine Skip to main content The New England
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Acute liver failure is a rare and severe consequence of abrupt hepatocyte injury, and can
evolve over days or weeks to a lethal outcome. A variety of insults to liver cells result in a …

Acute liver failure is a rare disorder with high mortality and resource cost. In the developing
world, viral causes predominate, with hepatitis E infection recognised as a common cause in …

Abbreviated pathogenesis and clinical course of the acute liver failure syndrome. The
pathogenesis and clinical course of the syndrome of acute liver failure (ALF) differs …

The present version of the American Association for the Study of Liver Diseases (AASLD)
Position Paper represents a thorough overhaul from the previous version of 2005. In …

Liver failure affects brain function, leading to neurological and psychiatric alterations; such
alterations are referred to as hepatic encephalopathy (HE). Early diagnosis of minimal HE …

Acute liver failure (ALF) is a rare but challenging clinical syndrome with multiple causes; a
specific etiology cannot be identified in 15% of adult and 50% of pediatric cases. The course …

Increasing evidence suggests that induction of mild hypothermia (32–35° C) in the first hours
after an ischaemic event can prevent or mitigate permanent injuries. This effect has been …

Acute liver failure (ALF) describes a clinical syndrome of rapid hepatocyte injury leading to
liver failure manifested by coagulopathy and encephalopathy in the absence of pre-existing …

High circulating ammonia concentrations are common in patients with acute liver failure
(ALF) and are associated with hepatic encephalopathy (HE) and intracranial hypertension …