The bacterial epigenome

MA Sánchez-Romero, J Casadesús - Nature Reviews Microbiology, 2020 - nature.com
In all domains of life, genomes contain epigenetic information superimposed over the
nucleotide sequence. Epigenetic signals control DNA–protein interactions and can cause …

Beyond restriction modification: epigenomic roles of DNA methylation in prokaryotes

BP Anton, RJ Roberts - Annual Review of Microbiology, 2021 - annualreviews.org
The amount of bacterial and archaeal genome sequence and methylome data has greatly
increased over the last decade, enabling new insights into the functional roles of DNA …

Epigenetic regulation of virulence and immunoevasion by phase-variable restriction-modification systems in bacterial pathogens

KL Seib, YN Srikhanta, JM Atack… - Annual Review of …, 2020 - annualreviews.org
Human-adapted bacterial pathogens use a mechanism called phase variation to randomly
switch the expression of individual genes to generate a phenotypically diverse population to …

Bacterial DNA methyltransferase: A key to the epigenetic world with lessons learned from proteobacteria

Q Gao, S Lu, Y Wang, L He, M Wang, R Jia… - Frontiers in …, 2023 - frontiersin.org
Epigenetics modulates expression levels of various important genes in both prokaryotes and
eukaryotes. These epigenetic traits are heritable without any change in genetic DNA …

Phasevarions of bacterial pathogens–phase-variable epigenetic regulators evolving from restriction–modification systems

ZN Phillips, AU Husna, MP Jennings… - …, 2019 - microbiologyresearch.org
Phase-variable DNA methyltransferases control the expression of multiple genes via
epigenetic mechanisms in a wide variety of bacterial species. These systems are called …

Diversity of endophytic bacterial and fungal microbiota associated with the medicinal lichen Usnea longissima at high altitudes

Q Wang, J Li, J Yang, Y Zou, XQ Zhao - Frontiers in Microbiology, 2022 - frontiersin.org
Endophytic microbial communities of lichen are emerging as novel microbial resources and
for exploration of potential biotechnological applications. Here, we focused on a medicinal …

Acquisition of Type I methyltransferase via horizontal gene transfer increases the drug resistance of Aeromonas veronii

J Ma, H Zhao, S Mo, J Li, X Ma, Y Tang… - Microbial …, 2023 - microbiologyresearch.org
Aeromonas veronii is an opportunistic pathogen that affects both fish and mammals,
including humans, leading to bacteraemia, sepsis, meningitis and even death. The …

Actinobacillus pleuropneumoniae encodes multiple phase-variable DNA methyltransferases that control distinct phasevarions

N Nahar, G Tram, FEC Jen, ZN Phillips… - Nucleic Acids …, 2023 - academic.oup.com
Actinobacillus pleuropneumoniae is the cause of porcine pleuropneumonia, a severe
respiratory tract infection that is responsible for major economic losses to the swine industry …

The Moraxella catarrhalis phase-variable DNA methyltransferase ModM3 is an epigenetic regulator that affects bacterial survival in an in vivo model of otitis media

LV Blakeway, A Tan, JA Jurcisek, LO Bakaletz… - BMC microbiology, 2019 - Springer
Background Moraxella catarrhalis is a leading cause of otitis media (OM) and chronic
obstructive pulmonary disease (COPD). M. catarrhalis contains a Type III DNA adenine …

Panel 7–pathogenesis of otitis media–a review of the literature between 2015 and 2019

RB Thornton, A Hakansson, DW Hood… - International journal of …, 2020 - Elsevier
Objective To perform a comprehensive review of the literature from July 2015 to June 2019
on the pathogenesis of otitis media. Bacteria, viruses and the role of the microbiome as well …