Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …

It is well admitted that the link between chronic inflammation and cancer involves cytokines
and mediators of inflammatory pathways, which act during the different steps of …

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly used drugs in
inflammatory diseases, since they are effective in management of pain, fever, redness …

Pain Assessment and Pharmacologic Management, by highly renowned authors Chris
Pasero and Margo McCaffery, is destined to become the definitive resource in pain …

Osteoarthritis is a common rheumatologic disorder. It is estimated that 40 million Americans
and 70 to 90 percent of persons older than 75 years are affected by osteoarthritis. Although …

Conventional nonsteroidal antiinflammatory drugs (NSAIDs) are associated with acute renal
failure, but cyclooxygenase-2 inhibitors have not been comparatively evaluated. The authors …

NSAIDs are commonly used drugs. Even with the advent of selective COX-2 inhibitors,
nephrotoxicity still remains a concern. The adverse effects of NSAIDs are mediated via …

Pain has been recognized as a problem of global proportions, and postoperative pain is one
of the most common types of pain. Postoperative pain is acute and, although it is …

Purpose To compare two recently proposed Bayesian methods for quantitative
pharmacovigilance with respect to assumptions and results, and to describe some practical …

Objectives To compare the risk of death and recurrent congestive heart failure in elderly
patients prescribed celecoxib, rofecoxib, or non-steroidal anti-inflammatory drugs (NSAIDs) …