Rheumatoid arthritis (RA) is a systemic autoimmune disease that predominantly affects the
joints. The prevalence of RA varies globally, with generally a higher prevalence in …

Autoimmune diseases are a diverse group of conditions characterized by aberrant B cell
and T cell reactivity to normal constituents of the host. These diseases occur widely and …

The prevalence of autoimmune diseases (ADs) worldwide has rapidly increased over the
past few decades. Thus, in addition to the classical risk factors for ADs, such as genetic …

Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …

The gut microbiome, ie, the community of bacteria and other microorganisms living in the
human gut, has been implicated both directly and indirectly (mediating the effects of diet) on …

Identifying differentially abundant microbes is a common goal of microbiome studies.
Multiple methods are used interchangeably for this purpose in the literature. Yet, there are …

The genus Prevotella includes more than 50 characterized species that occur in varied
natural habitats, although most Prevotella spp. are associated with humans. In the human …

The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

The mucosal origins hypothesis of rheumatoid arthritis (RA) proposes a central role for
mucosal immune responses in the initiation or perpetuation of the systemic autoimmunity …

Changes in gut microbiota have been associated with several diseases. Here, the
International Multiple Sclerosis Microbiome Study (iMSMS) studied the gut microbiome of …