The blastocyst forms during the first days of mammalian development. The structure of the
blastocyst is conserved among placental mammals and is paramount to the establishment of …

During embryonic development, cells shape our body, which is mostly made up of water. It is
often forgotten that some of this water is found in intercellular fluid, which, for example …

Decades of research have not yet fully explained the mechanisms of epithelial self-
organization and 3D packing. Single-cell analysis of large 3D epithelial libraries is crucial for …

Assisted Reproductive Technologies (ART) have revolutionized infertility treatment and
animal breeding, but their success largely depends on selecting high-quality oocytes for …

The trophectoderm (TE) is the first tissue to differentiate during the preimplantation
development of the mammalian embryo. It forms the outer layer of the blastocyst and is …

Biomechanics in embryogenesis is a dynamic field intertwining the physical forces and
biological processes that shape the first days of a mammalian embryo. From the first cell fate …

How pattern and form are generated in a reproducible manner during embryogenesis
remains poorly understood. Intestinal organoid morphogenesis involves a number of …

Compaction is the first morphogenetic movement of the eutherian mammals and involves a
developmentally regulated adhesion process. Previous studies investigated cellular and …