Inflammation has been implicated in atrial fibrillation (AF), a very common and clinically
significant cardiac rhythm disturbance, but its precise role remains poorly understood. Work …

Diabetes mellitus is a metabolic disorder that majorly affects the endocrine gland, and it is
symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory …

Lipoxygenases (LOXs) are dioxygenases that catalyze the formation of corresponding
hydroperoxides from polyunsaturated fatty acids such as linoleic acid and arachidonic acid …

Despite the development of novel targeted drugs, the molecular heterogeneity of diffuse
large B-cell lymphoma (DLBCL) still poses a substantial therapeutic challenge. DLBCL can …

Technological and computational advances in genomics and interactomics have made it
possible to identify how disease mutations perturb protein–protein interaction (PPI) networks …

An effective host defense mechanism involves inflammation to eliminate pathogens from the
site of infection, followed by the resolution of inflammation and the restoration of tissue …

The synthesis of both proinflammatory leukotrienes and anti-inflammatory lipoxins requires
the enzyme 5-lipoxygenase (5-LOX). 5-LOX activity is short-lived, apparently in part because …

As the COVID-19 pandemic is progressing, the therapeutic gaps in conventional
management have highlighted the need for the integration of traditional knowledge systems …

Reactive species are highly-reactive enzymatically, or non-enzymatically produced
compounds with important roles in physiological and pathophysiological cellular processes …

5‐Lipoxygenase (ALOX5) is an iron‐containing and nonheme dioxygenase that catalyzes
the peroxidation of polyunsaturated fatty acids such as arachidonic acid. ALOX5 is the rate …