Survey of the year 2007 commercial optical biosensor literature
RL Rich, DG Myszka - Journal of Molecular Recognition: An …, 2008 - Wiley Online Library
In 2007, 1179 papers were published that involved the application of optical biosensors.
Reported developments in instrument hardware, assay design, and immobilization …
Reported developments in instrument hardware, assay design, and immobilization …
The RelA/SpoT homolog (RSH) superfamily: distribution and functional evolution of ppGpp synthetases and hydrolases across the tree of life
GC Atkinson, T Tenson, V Hauryliuk - PloS one, 2011 - journals.plos.org
RelA/SpoT Homologue (RSH) proteins, named for their sequence similarity to the RelA and
SpoT enzymes of Escherichia coli, comprise a superfamily of enzymes that synthesize …
SpoT enzymes of Escherichia coli, comprise a superfamily of enzymes that synthesize …
Tale of Twin Bifunctional Second Messenger (p) ppGpp Synthetases and Their Function in Mycobacteria
M. tuberculosis, an etiological agent of tuberculosis, requires a long treatment regimen due
to its ability to respond to stress and persist inside the host. The second messenger (p) …
to its ability to respond to stress and persist inside the host. The second messenger (p) …
The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis
S Arenz, M Abdelshahid, D Sohmen… - Nucleic acids …, 2016 - academic.oup.com
Under stress conditions, such as nutrient starvation, deacylated tRNAs bound within the
ribosomal A-site are recognized by the stringent factor RelA, which converts ATP and …
ribosomal A-site are recognized by the stringent factor RelA, which converts ATP and …
Synthetic (p) ppGpp analogue is an inhibitor of stringent response in mycobacteria
Bacteria elicit an adaptive response against hostile conditions such as starvation and other
kinds of stresses. Their ability to survive such conditions depends, in part, on stringent …
kinds of stresses. Their ability to survive such conditions depends, in part, on stringent …
An intramolecular cross-talk in D29 mycobacteriophage endolysin governs the lytic cycle and phage-host population dynamics
G Nair, V Jain - Science Advances, 2024 - science.org
D29 mycobacteriophage encodes LysA endolysin, which mediates mycobacterial host cell
lysis by targeting its peptidoglycan layer, thus projecting itself as a potential therapeutic …
lysis by targeting its peptidoglycan layer, thus projecting itself as a potential therapeutic …
Insights into the virulence of oral biofilms: discoveries from proteomics
M Kuboniwa, GD Tribble, EL Hendrickson… - Expert review of …, 2012 - Taylor & Francis
This review covers developments in the study of polymicrobial communities, biofilms and
selected areas of host response relevant to dental plaque and related areas of oral biology …
selected areas of host response relevant to dental plaque and related areas of oral biology …
The stringent response and Mycobacterium tuberculosis pathogenesis
J Prusa, DX Zhu, CL Stallings - Pathogens and disease, 2018 - academic.oup.com
During infection, the host restrains Mycobacterium tuberculosis (Mtb) from proliferating by
imposing an arsenal of stresses. Despite this onslaught of attacks, Mtb is able to persist for …
imposing an arsenal of stresses. Despite this onslaught of attacks, Mtb is able to persist for …
RelZ-Mediated Stress Response in Mycobacterium smegmatis: pGpp Synthesis and Its Regulation
Stringent response is a conserved stress response mechanism in which bacteria employ the
second messengers guanosine tetraphosphate and guanosine pentaphosphate [collectively …
second messengers guanosine tetraphosphate and guanosine pentaphosphate [collectively …
Uncovering mechanisms of bistability in biological systems
JR Pomerening - Current opinion in biotechnology, 2008 - Elsevier
As the systems biology era progresses, theoreticians and experimentalists continue
uncovering the molecular mechanisms that underlie the regulation of complex cellular …
uncovering the molecular mechanisms that underlie the regulation of complex cellular …