Recent advances in single-cell analysis by mass spectrometry

L Yin, Z Zhang, Y Liu, Y Gao, J Gu - Analyst, 2019 - pubs.rsc.org
Cells are the most basic structural units that play vital roles in the functioning of living
organisms. Analysis of the chemical composition and content of a single cell plays a vital …

Perspective on ferroelectric devices: lessons from interfacial chemistry

K Yang, SH Kim, HW Jeong, DH Lee… - Chemistry of …, 2023 - ACS Publications
Ferroelectric fluorite-structured oxide thin films have attracted increased interest from both
academia and industry because of their superior scalability─ in which their ferroelectric …

Single-cell metabolic profiling of macrophages using 3D OrbiSIMS: correlations with phenotype

W Suvannapruk, MK Edney, DH Kim, DJ Scurr… - Analytical …, 2022 - ACS Publications
Macrophages are important immune cells that respond to environmental cues acquiring a
range of activation statuses represented by pro-inflammatory (M1) and anti-inflammatory …

Lipidome atlas of the adult human brain

M Osetrova, A Tkachev, W Mair… - Nature …, 2024 - nature.com
Lipids are the most abundant but poorly explored components of the human brain. Here, we
present a lipidome map of the human brain comprising 75 regions, including 52 neocortical …

Time-of-flight secondary ion mass spectrometry coupled with unsupervised methods for advanced saffron authenticity screening

E De Angelis, O Al-Ayoubi, R Pilolli, L Monaci… - Foods, 2024 - mdpi.com
Saffron, renowned for its aroma and flavor, is susceptible to adulteration due to its high value
and demand. Current detection methods, including ISO standards, often fail to identify …

Three dimensional secondary ion mass spectrometry imaging (3D-SIMS) of Aedes aegypti ovarian follicles

A Castellanos, CE Ramirez, V Michalkova… - Journal of analytical …, 2019 - pubs.rsc.org
The mobilization of nutrient reserves into the ovaries of Aedes aegypti mosquitoes after
sugar-feeding plays a vital role in the female's reproductive maturation. In the present work …

Exploiting the semidestructive nature of gas cluster ion beam time-of-flight secondary ion mass spectrometry imaging for simultaneous localization and confident lipid …

TB Angerer, D Velickovic, CD Nicora, JE Kyle… - Analytical …, 2019 - ACS Publications
Lipids have been recognized as key players in cell signaling and disease. Information on
their location and distribution within a biological system, under varying conditions, is …

(CO2)n+, (H2O)n+, and (H2O)n+ (CO2) gas cluster ion beam secondary ion mass spectrometry: analysis of lipid extracts, cells, and Alzheimer's model …

K Dimovska Nilsson, A Karagianni, I Kaya… - Analytical and …, 2021 - Springer
This work assesses the potential of new water cluster-based ion beams for improving the
capabilities of secondary ion mass spectrometry (SIMS) for in situ lipidomics. The effect of …

Multimodal, in situ imaging of ex vivo human skin reveals decrease of cholesterol sulfate in the neoepithelium during acute wound healing

A Castellanos, MG Hernandez, M Tomic-Canic… - Analytical …, 2019 - ACS Publications
Skin repair is a significant aspect of human health. While the makeup of healthy stratum
corneum and epidermis is generally understood, the mobilization of molecular components …

[HTML][HTML] (CO2) n+,(H2O) n+, and (H2O) n+ (CO2) gas cluster ion beam secondary ion mass spectrometry: analysis of lipid extracts, cells, and Alzheimer's model …

KD Nilsson, A Karagianni, I Kaya… - Analytical and …, 2021 - ncbi.nlm.nih.gov
This work assesses the potential of new water cluster-based ion beams for improving the
capabilities of secondary ion mass spectrometry (SIMS) for in situ lipidomics. The effect of …