Background Rearrangements of the histone‐lysine‐N‐methyltransferase (KMT2A),
previously referred to as mixed‐lineage leukemia (MLL), are among the most common …

Acute megakaryoblastic leukemia (AMKL) is a rare subtype of acute myeloid leukemia
(AML) in which leukemic blasts have megakaryocytic features. AMKL makes up 4%–15% of …

The fornix is a white matter bundle located in the center of the hippocampaldiencephalic
limbic circuit that controls memory and executive functions, yet its genetic architectures and …

Long noncoding RNAs (lncRNAs), as gene expression modulators, are potential players in
Acute Lymphoblastic Leukemia (ALL) pathogenesis. We systematically explored current …

A t (9; 11)(p22; q23) translocation produces the MLL-AF9 fusion protein, which is found in up
to 25% of de novo AML cases in children. Despite major advances, obtaining a …

The ubiquitin‑proteasome system is a major degradation pathway for> 80% of proteins in
vivo. Deubiquitylases, which remove ubiquitinated tags to stabilize substrate proteins, are …

Background Hepatocellular carcinoma (HCC) is a common malignant tumor. There are few
studies on EXOSC10 (exosome component 10) in HCC; however, the importance of …

Acute myeloid leukemia (AML) presents an unpredictable and complex prognosis.
Researchers have been exploring different ways to determine the death of cancer cells …

Hiermit erkläre ich, die Dissertation mit dem Titel „Fluoreszenzin-situ-Hybridisierung und
funktionelle Analyse der KMT2AMAML2 Translokation in epithelialen Thymusneoplasien …

Ataxia telangiectasia mutated (ATM) blockage can induce apoptosis in ovarian cancer.
However, the molecular mechanisms responsible for the processes remain poorly …