RNA-binding proteins in tumor progression

H Qin, H Ni, Y Liu, Y Yuan, T Xi, X Li… - Journal of hematology & …, 2020 - Springer
RNA-binding protein (RBP) has a highly dynamic spatiotemporal regulation process and
important biological functions. They are critical to maintain the transcriptome through post …

miRNAs as cornerstones in colorectal cancer pathogenesis and resistance to therapy: A spotlight on signaling pathways interplay—A review

MA Elrebehy, S Al-Saeed, S Gamal, A El-Sayed… - International journal of …, 2022 - Elsevier
Colorectal cancer (CRC) is the world's third most prevalent cancer and the main cause of
cancer-related mortality. A lot of work has been put into improving CRC patients' clinical …

[HTML][HTML] Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19

J Ren, L Ding, D Zhang, G Shi, Q Xu, S Shen… - Theranostics, 2018 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) are involved in the pathology of various tumors, including
colorectal cancer (CRC). The crosstalk between carcinoma-associated fibroblasts (CAFs) …

Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer

K Wu, J Feng, F Lyu, F Xing, S Sharma, Y Liu… - Nature …, 2021 - nature.com
Bone metastasis is an incurable complication of breast cancer. In advanced stages, patients
with estrogen-positive tumors experience a significantly higher incidence of bone metastasis …

The role of tumor necrosis factor in manipulating the immunological response of tumor microenvironment

D Laha, R Grant, P Mishra, N Nilubol - Frontiers in immunology, 2021 - frontiersin.org
The tumor microenvironment (TME) is an intricate system within solid neoplasms. In this
review, we aim to provide an updated insight into the TME with a focus on the effects of …

Small extracellular vesicles from young plasma reverse age-related functional declines by improving mitochondrial energy metabolism

X Chen, Y Luo, Q Zhu, J Zhang, H Huang, Y Kan, D Li… - Nature Aging, 2024 - nature.com
Recent investigations into heterochronic parabiosis have unveiled robust rejuvenating
effects of young blood on aged tissues. However, the specific rejuvenating mechanisms …

Decreased inhibition of exosomal miRNAs on SARS-CoV-2 replication underlies poor outcomes in elderly people and diabetic patients

Y Wang, X Zhu, XM Jiang, J Guo, Z Fu, Z Zhou… - … and Targeted Therapy, 2021 - nature.com
Elderly people and patients with comorbidities are at higher risk of COVID-19 infection,
resulting in severe complications and high mortality. However, the underlying mechanisms …

The impact of miRNA in colorectal cancer progression and its liver metastases

O Balacescu, D Sur, C Cainap, S Visan… - International journal of …, 2018 - mdpi.com
Colorectal cancer (CRC) is one of the most commonly diagnosed malignancies with a high
incidence and mortality rate. An essential challenge in colorectal cancer management is to …

Novel strategies to reverse chemoresistance in colorectal cancer

SC Ma, JQ Zhang, TH Yan, MX Miao, YM Cao… - Cancer …, 2023 - Wiley Online Library
Colorectal cancer (CRC) is a common gastrointestinal malignancy with high morbidity and
fatality. Chemotherapy, as traditional therapy for CRC, has exerted well antitumor effect and …

Identification of a six‐miRNA panel in serum benefiting pancreatic cancer diagnosis

X Zou, J Wei, Z Huang, X Zhou, Z Lu, W Zhu… - Cancer …, 2019 - Wiley Online Library
Pancreatic cancer (PC) has posed a great health threat to a growing number of people all
over the world. Detection of serum miRNAs, being sensitive, noninvasive, and easy to …