Novel 7-chloro-4-aminoquinoline-benzimidazole hybrids as inhibitors of cancer cells growth: synthesis, antiproliferative activity, in silico ADME predictions, and …
In this study, new 7-chloro-4-aminoquinoline-benzimidazole compounds were synthesized
and characterized by NMR, MS, and elemental analysis. These novel hybrids differ in the …
and characterized by NMR, MS, and elemental analysis. These novel hybrids differ in the …
Synthesis of boronated amidines by addition of amines to nitrilium derivative of cobalt bis (dicarbollide)
EV Bogdanova, MY Stogniy, KY Suponitsky, IB Sivaev… - Molecules, 2021 - mdpi.com
A series of novel cobalt bis (dicarbollide) based amidines were synthesized by the
nucleophilic addition of primary and secondary amines to highly activated B-N+≡ C–R triple …
nucleophilic addition of primary and secondary amines to highly activated B-N+≡ C–R triple …
Rhodanine Derivatives as Anticancer Agents: QSAR and Molecular Docking Studies
M Molnar, M Lončarić… - Anti-Cancer Agents …, 2023 - ingentaconnect.com
Background: Rhodanine derivatives have a proven wide range of biological activities.
Objective: The aim of this study was to evaluate the cytotoxic effect of a series of rhodanine …
Objective: The aim of this study was to evaluate the cytotoxic effect of a series of rhodanine …
Recent Advances in Discovery of New Tyrosine Kinase Inhibitors Using Computational Methods
Tyrosine kinases are enzymes that phosphorylate tyrosine residues in specific substrates,
and their activities are involved in the pathophysiology of cancer. The inhibitors of tyrosine …
and their activities are involved in the pathophysiology of cancer. The inhibitors of tyrosine …
Effects of quinoline-arylamidine hybrids on LPS-induced inflammation in RAW 264.7 cells
A Periš, M Jukić, L Krstulović, M Bajić… - Periodicum …, 2020 - hrcak.srce.hr
Background and purpose: Inflammation is a common pathogenesis in infection, injury,
cancer, and many chronic diseases. Macrophages are among the main cells involved in …
cancer, and many chronic diseases. Macrophages are among the main cells involved in …