Influenza neuraminidase

GM Air - Influenza and other respiratory viruses, 2011 - pmc.ncbi.nlm.nih.gov
Please cite this paper as: Air.(2012) Influenza neuraminidase. Influenza and Other
Respiratory Viruses 6 (4), 245–256. Influenza neuraminidase is the target of two licensed …

[图书][B] Immunology and evolution of infectious disease

SA Frank - 2002 - degruyter.com
From HIV to influenza, the battle between infectious agents and the immune system is at the
heart of disease. Knowledge of how and why parasites vary to escape recognition by the …

Mesoscale all-atom influenza virus simulations suggest new substrate binding mechanism

JD Durrant, SE Kochanek, L Casalino… - ACS central …, 2020 - ACS Publications
Influenza virus circulates in human, avian, and swine hosts, causing seasonal epidemic and
occasional pandemic outbreaks. Influenza neuraminidase, a viral surface glycoprotein, has …

Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase

R Lei, W Kim, H Lv, Z Mou, MJ Scherm, AJ Schmitz… - Immunity, 2023 - cell.com
There is growing appreciation for neuraminidase (NA) as an influenza vaccine target;
however, its antigenicity remains poorly characterized. In this study, we isolated three …

The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor

JN Varghese, JL McKimm‐Breschkin… - Proteins: Structure …, 1992 - Wiley Online Library
Crystallographic studies of neuraminidase–sialic acid complexes indicate that sialic acid is
distorted on binding the enzyme. Three arginine residues on the enzyme interact with the …

Influenza virus neuraminidase: structure, antibodies, and inhibitors

PM Colman - Protein Science, 1994 - Wiley Online Library
The determination of the 3‐dimensional structure of the influenza virus neuraminidase in
1983 has served as a platform for understanding interactions between antibodies and …

A perspective on the structural and functional constraints for immune evasion: insights from influenza virus

NC Wu, IA Wilson - Journal of molecular biology, 2017 - Elsevier
Influenza virus evolves rapidly to constantly escape from natural immunity. Most humoral
immune responses to influenza virus target the hemagglutinin (HA) glycoprotein, which is …

The neuraminidase of influenza virus

GM Air, WG Laver - Proteins: Structure, Function, and …, 1989 - Wiley Online Library
It is the enzyme neuraminidase, projecting form the surface of influenza virus particles,
which allows the virus to leave infected cells and spread in the body. Antibodies which …

Is the gene pool of influenza viruses in shorebirds and gulls different from that in wild ducks?

Y Kawaoka, TM Chambers, WL Sladen, R Gwebster - Virology, 1988 - Elsevier
Evidence is presented for a second major gene pool of influenza A viruses in nature.
Shorebirds and gulls harbor influenza viruses when sampled in the spring and fall …

Infection and tissue distribution of highly pathogenic avian influenza A type H5N1 (clade 2.3.4.4b) in red fox kits (Vulpes vulpes)

BD Cronk, LC Caserta, M Laverack… - Emerging Microbes & …, 2023 - Taylor & Francis
Avian influenza H5N1 is a highly pathogenic virus that primarily affects birds. However, it
can also infect other animal species, including mammals. We report the infection of nine …