Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Organic photosensitizers for antimicrobial phototherapy

VN Nguyen, Z Zhao, BZ Tang, J Yoon - Chemical Society Reviews, 2022 - pubs.rsc.org
Microbial infectious diseases, especially those caused by new and antibiotic-resistant
pathogenic microbes, have become a significant threat to global human health. As an …

Advanced biotechnology-assisted precise sonodynamic therapy

Y Zhang, X Zhang, H Yang, L Yu, Y Xu… - Chemical Society …, 2021 - pubs.rsc.org
Despite significant advances, the therapeutic impact of photodynamic therapy is still
substantially hampered by the restricted penetration depth of light and the reactive oxygen …

BODIPY as a Multifunctional Theranostic Reagent in Biomedicine: Self‐Assembly, Properties, and Applications

HB Cheng, X Cao, S Zhang, K Zhang… - Advanced …, 2023 - Wiley Online Library
The use of boron dipyrromethene (BODIPY) in biomedicine is reviewed. To open, its
synthesis and regulatory strategies are summarized, and inspiring cutting‐edge work in post …

Phototherapeutic anticancer strategies with first-row transition metal complexes: a critical review

L Gourdon, K Cariou, G Gasser - Chemical Society Reviews, 2022 - pubs.rsc.org
Photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) are therapeutic
techniques based on a photosensitizer (PS) and light. These techniques allow the spatial …

BODIPY‐based photodynamic agents for exclusively generating superoxide radical over singlet oxygen

KX Teng, WK Chen, LY Niu, WH Fang… - Angewandte Chemie …, 2021 - Wiley Online Library
Developing Type‐I photosensitizers is considered as an efficient approach to overcome the
deficiency of traditional photodynamic therapy (PDT) for hypoxic tumors. However, it remains …

Mitochondria-targeted smart AIEgens: Imaging and therapeutics

H Li, H Kim, C Zhang, S Zeng, Q Chen, L Jia… - Coordination Chemistry …, 2022 - Elsevier
Mitochondria are not only the main energy source of the cell but are also involved in the
regulation of important physiology and processes of diseases including cancers. Therefore …

Golgi apparatus-targeted aggregation-induced emission luminogens for effective cancer photodynamic therapy

M Liu, Y Chen, Y Guo, H Yuan, T Cui, S Yao… - Nature …, 2022 - nature.com
Golgi apparatus (GA) oxidative stress induced by in situ reactive oxygen species (ROS)
could severely damage the morphology and function of GA, which may open up an avenue …

Activatable nano-photosensitizers for precise photodynamic cancer therapy

Z Li, Z Zhou, Y Wang, J Wang, L Zhou… - Coordination Chemistry …, 2023 - Elsevier
Owing to the excellent cell ablation ability and low side effects, photodynamic therapy (PDT)
plays an important role in disease treatment, especially cancer. However, most PDT agents …

Manipulating exciton dynamics toward simultaneous high-efficiency narrowband electroluminescence and photon upconversion by a selenium-incorporated …

X Cao, K Pan, J Miao, X Lv, Z Huang, F Ni… - Journal of the …, 2022 - ACS Publications
Multiresonance thermal activated delayed fluorescence (MR-TADF) materials with an
efficient spin–flip transition between singlet and triplet excited states remain demanding …