Primary sclerosing cholangitis (PSC) is a rare disorder characterised by multi-focal bile duct
strictures and progressive liver disease. Inflammatory bowel disease is usually present and …

Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by
intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis. Inflammation and …

Non-invasive tests are increasingly being used to improve the diagnosis and
prognostication of chronic liver diseases across aetiologies. Herein, we provide the latest …

Management of primary or secondary sclerosing cholangitis is challenging. These Clinical
Practice Guidelines have been developed to provide practical guidance on debated topics …

Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALP, alkaline phosphatase; ASIR, age standardized incidence rate; …

Chronic liver diseases often result in the development of liver fibrosis and ultimately,
cirrhosis. Treatment strategies and prognosis differ greatly depending on the severity of liver …

Introduction: Non-invasive assessment of fibrosis is increasingly utilized in clinical practice
to diagnose hepatic fibrosis. Non-invasive assessment of liver fibrosis relies on biologic …

Conclusions: LSM from TE, shear wave elastography, and MRE shows acceptable to
outstanding accuracy for the detection of liver fibrosis across various liver disease etiologies …

Improved methods are needed to risk stratify and predict outcomes in patients with primary
sclerosing cholangitis (PSC). Therefore, we sought to derive and validate a prediction model …

Although patients with PSC are increasingly diagnosed at earlier stages of disease based
on asymptomatic serum liver enzyme abnormalities, at least 45% of patients PSC present …