Blood and plasma are the biomatrices traditionally used for drug monitoring and their
pharmacokinetic profiling. Blood is the circulating fluid in contact with all organs and tissues …

Bacterial and fungal co-infection leads to polymicrobial keratitis (PMK). The current study
produced swellable mucoadhesive biopolymeric films composed of chitosan, HPMC, and …

Ocular drug delivery is a very challenging task faced by pharmaceutical scientists, inspire of
the fact that eye is the most sensitive and accessible organ for the delivery of drugs. A major …

The aim of this research was to evaluate the potential use of in situ gel formulations for
voriconazole ocular delivery as fungal keratitis treatment. The in situ gelling system was …

The expansion of polymicrobial keratomycosis (PMK) requires dynamic pharmacotherapy of
antimycotics along with antibacterial agents such as fluconazole (FCZ) and ofloxacin (OFX) …

Polymeric films were prepared based on chitosan and its blends with poly (2-ethyl-2-
oxazoline) by casting from aqueous solutions. These materials were characterised using a …

A simple, fast, and responsive liquid chromatography‐tandem mass spectrometry method
was established and fully validated according to the United States Food and Drug …

Ocular allergy is one of the most common disorders of the eye surface. The conventional eye
drops lack of therapeutic efficacy due to low ocular bioavailability and decreased drug …

Introduction Allergic eye diseases includes a spectrum of diseases, with each state being
characterized by a complicated immunopathology. In the present study, polymeric Kollidon® …

Novel macromolecular prodrugs of the second-generation fluoroquinolone antibiotic
ofloxacin were fabricated based on the hydrophilic biopolymers hydroxypropylcellulose …