Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies

S Xu, I Ilyas, J Weng - Acta Pharmacologica Sinica, 2023 - nature.com
The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …

Nitric oxide signalling in kidney regulation and cardiometabolic health

M Carlström - Nature reviews nephrology, 2021 - nature.com
The prevalence of cardiovascular and metabolic disease coupled with kidney dysfunction is
increasing worldwide. This triad of disorders is associated with considerable morbidity and …

Implication of COVID-19 on erythrocytes functionality: red blood cell biochemical implications and morpho-functional aspects

A Russo, E Tellone, D Barreca, S Ficarra… - International journal of …, 2022 - mdpi.com
Several diseases (such as diabetes, cancer, and neurodegenerative disorders) affect the
morpho-functional aspects of red blood cells, sometimes altering their normal metabolism. In …

Mitochondrial dynamics in SARS-COV2 spike protein treated human microglia: implications for neuro-COVID

E Clough, J Inigo, D Chandra, L Chaves… - Journal of Neuroimmune …, 2021 - Springer
Emerging clinical data from the current COVID-19 pandemic suggests that~ 40% of COVID-
19 patients develop neurological symptoms attributed to viral encephalitis while in COVID …

[HTML][HTML] Decreased availability of nitric oxide and hydrogen sulfide is a hallmark of COVID-19

P Dominic, J Ahmad, R Bhandari, S Pardue… - Redox biology, 2021 - Elsevier
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is involved in
a global outbreak affecting millions of people who manifest a variety of symptoms …

A chemiresistive ppt level NO2 gas sensor based on CeO2 nanoparticles modified CuO nanosheets operated at 100° C

H Fang, E Shang, D Wang, X Ma, B Zhao, C Han… - Sensors and Actuators B …, 2023 - Elsevier
Inducing chemisorbed oxygen and constructing heterostructures are important strategies for
improving sensors performance. Therefore, we prepared cupric oxide (CuO) composite …

Inhalation delivery for the treatment and prevention of COVID-19 infection

BB Eedara, W Alabsi, D Encinas-Basurto, R Polt… - Pharmaceutics, 2021 - mdpi.com
Coronavirus disease-2019 (COVID-19) is caused by coronavirus-2 (SARS-CoV-2) and has
produced a global pandemic. As of 22 June 2021, 178 million people have been affected …

Heparin prevents in vitro glycocalyx shedding induced by plasma from COVID-19 patients

SR Potje, TJ Costa, TFC Fraga-Silva, RB Martins… - Life sciences, 2021 - Elsevier
The severe forms and worsened outcomes of COVID-19 (coronavirus disease 19) are
closely associated with hypertension and cardiovascular disease. Endothelial cells express …

Regulation of pleiotropic physiological roles of nitric oxide signaling

L Soundararajan, A Dharmarajan, P Samji - Cellular signalling, 2023 - Elsevier
Nitric Oxide (NO) is a highly diffusible, ubiquitous signaling molecule and a free radical that
is naturally synthesized by our body. The pleiotropic effects of NO in biological systems are …

The nitration of proteins, lipids and DNA by peroxynitrite derivatives-chemistry involved and biological relevance

JM Pérez de la Lastra, CA Juan, FJ Plou… - Stresses, 2022 - mdpi.com
In recent years, much interest has been generated by the idea that nitrosative stress plays a
role in the aetiology of human diseases, such as atherosclerosis, inflammation, cancer, and …