Hydrogen peroxide (H2O2) is an important metabolite involved in most of the redox
metabolism reactions and processes of the cells. H2O2 is recognized as one of the main …

Over the last decade, studies have unraveled many aspects of endogenous production and
physiological functions of carbon monoxide (CO). The majority of endogenous CO is …

Abstract Heme oxygenase (HO)-1 catabolizes heme into three products: carbon monoxide
(CO), biliverdin (which is rapidly converted to bilirubin) and free iron (which leads to the …

Heme oxygenases are composed of two isozymes, Hmox1 and Hmox2, that catalyze the
degradation of heme to carbon monoxide (CO), ferrous iron, and biliverdin, the latter of …

Emerging evidence indicates that l-glutamine (Gln) plays a fundamental role in
cardiovascular physiology and pathology. By serving as a substrate for the synthesis of …

Carbon monoxide (CO) is emerging as an important and versatile mediator of physiological
processes to the extent that treatment of animals with exogenous CO gas has beneficial …

Carbon monoxide (CO), one of the products of heme oxygenase action on heme, prevents
arteriosclerotic lesions that occur following aorta transplantation; pre-exposure to 250 parts …

▪ Abstract Many biological functions of heme oxygenase (HO), such as cytoprotection
against oxidative stress, vasodilation, neurotransmission in the central or peripheral nervous …

Heme oxygenase-1 (HO-1) catalyzes the oxidation of heme to biologically active products:
carbon monoxide (CO), biliverdin, and ferrous iron. It participates in maintaining cellular …

Ischaemic heart disease is one of the leading causes of morbidity and mortality worldwide.
The development of cardioprotective therapeutic agents remains a partly unmet need and a …