Malaria chemoprevention and drug resistance: a review of the literature and policy implications

CV Plowe - Malaria Journal, 2022 - Springer
Chemoprevention strategies reduce malaria disease and death, but the efficacy of anti-
malarial drugs used for chemoprevention is perennially threatened by drug resistance. This …

[HTML][HTML] Plasmodium falciparum resistance to artemisinin-based combination therapies: A sword of Damocles in the path toward malaria elimination

M Ouji, JM Augereau, L Paloque, F Benoit-Vical - Parasite, 2018 - ncbi.nlm.nih.gov
The use of artemisinin-based combination therapies (ACTs), which combine an artemisinin
derivative with a partner drug, in the treatment of uncomplicated malaria has largely been …

Antimalarial drug resistance and implications for the WHO global technical strategy

MM Ippolito, KA Moser, JBB Kabuya… - Current epidemiology …, 2021 - Springer
Abstract Purpose of Review Five years have passed since the World Health Organization
released its Global Technical Strategy for Malaria (GTS). In that time, progress against …

The COVID-19 pandemic: A threat to antimicrobial resistance containment

RC Founou, AJ Blocker, M Noubom, C Tsayem… - Future Science …, 2021 - Taylor & Francis
As of 23 April 2021, the outbreak of COVID-19 claimed around 150 million confirmed cases
with over 3 million deaths worldwide. Yet, an even more serious but silent pandemic, that of …

Detection of mutations associated with artemisinin resistance at k13-propeller gene and a near complete return of chloroquine susceptible falciparum malaria in …

GM Bwire, B Ngasala, WP Mikomangwa, M Kilonzi… - Scientific Reports, 2020 - nature.com
In Tanzania, chloroquine was replaced by sulphadoxine-pyrimethamine (SP) as a first-line
for treatment of uncomplicated malaria. Due to high resistance in malaria parasites, SP …

[HTML][HTML] Fighting COVID-19 at the expense of malaria in Africa: the consequences and policy options

AT Aborode, KB David, O Uwishema… - The American Journal …, 2021 - ncbi.nlm.nih.gov
Malaria remains a major global health burden, killing hundreds of thousands annually,
especially in sub-Saharan Africa. In December 2019, a novel illness termed COVID-19 …

The genomic architecture of antimalarial drug resistance

AN Cowell, EA Winzeler - Briefings in functional genomics, 2019 - academic.oup.com
Plasmodium falciparum and Plasmodium vivax, the two protozoan parasite species that
cause the majority of cases of human malaria, have developed resistance to nearly all …

Pausing the fight against malaria to combat the COVID-19 pandemic in Africa: is the future of malaria bleak?

NN Nghochuzie, CO Olwal, AJ Udoakang… - Frontiers in …, 2020 - frontiersin.org
Malaria remains a major global health burden, killing hundreds of thousands annually,
especially in sub-Saharan Africa. In 2019, a Phase IV Expanded Programme on …

Chloroquine and sulfadoxine–pyrimethamine resistance in Sub-Saharan Africa—A review

AT Roux, L Maharaj, O Oyegoke, OP Akoniyon… - Frontiers in …, 2021 - frontiersin.org
Malaria is a great concern for global health and accounts for a large amount of morbidity and
mortality, particularly in Africa, with sub-Saharan Africa carrying the greatest burden of the …

Plasmodium genomics: an approach for learning about and ending human malaria

JA Garrido-Cardenas, L González-Cerón… - Parasitology …, 2019 - Springer
Malaria causes high levels of morbidity and mortality in human beings worldwide. According
to the World Health Organization (WHO), about half a million people die of this disease each …