Treatment for rotator cuff tear is influenced by demographics and characteristics of the area where patients live

CG Chapman, SB Floyd, CA Thigpen… - JBJS Open …, 2018 - journals.lww.com
Background: Atraumatic rotator cuff tear is a common orthopaedic complaint for people> 60
years of age. Lack of evidence or consensus on appropriate treatment for this type of injury …

Assessing the ability of an instrumental variable causal forest algorithm to personalize treatment evidence using observational data: the case of early surgery for …

JM Brooks, CG Chapman, SB Floyd, BK Chen… - BMC medical research …, 2022 - Springer
Background Comparative effectiveness research (CER) using observational databases has
been suggested to obtain personalized evidence of treatment effectiveness. Inferential …

Association of surgical treatment with adverse events and mortality among Medicare beneficiaries with proximal humerus fracture

SB Floyd, C Thigpen, M Kissenberth… - JAMA network …, 2020 - jamanetwork.com
Importance Meta-analyses of randomized clinical trials suggest that the advantages and
risks of surgery compared with conservative management as the initial treatment for …

Moving toward the next paradigm for cardiovascular prevention

JG Robinson, K Ray - Circulation, 2016 - Am Heart Assoc
1534 Circulation April 19, 2016 therapy at the ARR≥ 2.3% threshold. A more liberal ARR
threshold of≥ 1.5%(10-year NNT≤ 67; average 10-year NNT= 30), would treat 11 million …

Lipid testing trends before and after hospitalization for myocardial infarction among adults in the United States, 2008–2019

SN Levintow, SR Reading, S Noshad… - Clinical …, 2022 - Taylor & Francis
Background Routine monitoring of low-density lipoprotein cholesterol (LDL-C) identifies
patients who may benefit from modifying lipid-lowering therapies (LLT). However, the extent …

Understanding treatment effect estimates when treatment effects are heterogeneous for more than one outcome

JM Brooks, CG Chapman, MC Schroeder - Applied health economics and …, 2018 - Springer
Background Patient-centred care requires evidence of treatment effects across many
outcomes. Outcomes can be beneficial (eg increased survival or cure rates) or detrimental …

Generating Practice-Based Evidence in the Use of Guideline-Recommended Combination Therapy for Secondary Prevention of Acute Myocardial Infarction

MC Schroeder, CG Chapman, EA Chrischilles… - Pharmacy, 2022 - mdpi.com
Background: Clinical guidelines recommend beta-blockers, angiotensin-converting enzyme
inhibitors/angiotensin-receptor blockers, and statins for the secondary prevention of acute …

Cross-Sectoral Comparisons of Process Quality Indicators of Health Care Across Residential Regions Using Restricted Mean Survival Time

H Šinkovec, W Gall, G Heinze - Medical care, 2024 - journals.lww.com
Background: Practice guidelines recommend patient management based on scientific
evidence. Quality indicators gauge adherence to such recommendations and assess health …

[HTML][HTML] 模拟目标试验在真实世界中的应用: 他汀类药物对糖尿病患者死亡率的影响

王睿哲, 奚丽婧, 杨雪珂, 库超越, 吴彬彬, 代漫… - 中华流行病学 …, 2023 - html.rhhz.net
模拟目标试验是一种观察性研究方法, 该方法在无法进行随机对照试验(RCT) 的情况下,
可以利用真实世界数据(如观察性数据及历史性数据) 按照RCT 的设计原则进行研究设计 …

Use of Angiotensin‐Converting Enzyme Inhibitors and Angiotensin Receptor Blockers for Geriatric Ischemic Stroke Patients: Are the Rates Right?

JM Brooks, CG Chapman, M Suneja… - Journal of the …, 2018 - Am Heart Assoc
Background Our objective is to estimate the effects associated with higher rates of renin‐
angiotensin system antagonists, angiotensin‐converting enzyme inhibitors and angiotensin …