Background Comparative effectiveness research (CER) using observational databases has been suggested to obtain personalized evidence of treatment effectiveness. Inferential …
SB Floyd, C Thigpen, M Kissenberth… - JAMA network …, 2020 - jamanetwork.com
Importance Meta-analyses of randomized clinical trials suggest that the advantages and risks of surgery compared with conservative management as the initial treatment for …
1534 Circulation April 19, 2016 therapy at the ARR≥ 2.3% threshold. A more liberal ARR threshold of≥ 1.5%(10-year NNT≤ 67; average 10-year NNT= 30), would treat 11 million …
SN Levintow, SR Reading, S Noshad… - Clinical …, 2022 - Taylor & Francis
Background Routine monitoring of low-density lipoprotein cholesterol (LDL-C) identifies patients who may benefit from modifying lipid-lowering therapies (LLT). However, the extent …
Background Patient-centred care requires evidence of treatment effects across many outcomes. Outcomes can be beneficial (eg increased survival or cure rates) or detrimental …
Background: Clinical guidelines recommend beta-blockers, angiotensin-converting enzyme inhibitors/angiotensin-receptor blockers, and statins for the secondary prevention of acute …
H Šinkovec, W Gall, G Heinze - Medical care, 2024 - journals.lww.com
Background: Practice guidelines recommend patient management based on scientific evidence. Quality indicators gauge adherence to such recommendations and assess health …
Background Our objective is to estimate the effects associated with higher rates of renin‐ angiotensin system antagonists, angiotensin‐converting enzyme inhibitors and angiotensin …