PRL2 regulates neutrophil extracellular trap formation which contributes to severe malaria and acute lung injury

X Du, B Ren, C Li, Q Li, S Kan, X Wang, W Bai… - Nature …, 2024 - nature.com
Excessive host immune responses contribute to severe malaria with high mortality. Here, we
show that PRL2 in innate immune cells is highly related to experimental malaria disease …

Experimental models to study the pathogenesis of malaria-associated acute respiratory distress syndrome

SYT Nguee, JWBD Júnior, S Epiphanio… - Frontiers in Cellular …, 2022 - frontiersin.org
Malaria-associated acute respiratory distress syndrome (MA-ARDS) is increasingly gaining
recognition as a severe malaria complication because of poor prognostic outcomes, high …

Blockage of mechanosensitive Piezo1 channel alleviates the severity of experimental malaria-associated acute lung injury

M Zhang, QR Wang, X Hou, Q Wang, X Yang, T Zhou… - Parasites & …, 2024 - Springer
Background Malaria-associated acute lung injury (MA-ALI) is a well-recognized clinical
complication of severe, complicated malaria that is partly driven by sequestrations of …

Single cell RNA sequencing reveals endothelial cell killing and resolution pathways in experimental malaria-associated acute respiratory distress syndrome

E Pollenus, H Possemiers, S Knoops, F Prenen… - Plos …, 2024 - journals.plos.org
Plasmodium parasites cause malaria, a global health disease that is responsible for more
than 200 million clinical cases and 600 000 deaths each year. Most deaths are caused by …

A bibliometric analysis of programmed cell death in acute lung injury/acute respiratory distress syndrome from 2000 to 2022

E Huang, L Gao, R Yu, K Xu, L Wang - Heliyon, 2023 - cell.com
Acute lung injury (ALI) is a prevalent critical disorder that disrupts the body's homeostasis in
patients. The progression from ALI to acute respiratory distress syndrome (ARDS) is often …

In vitro model of brain endothelial cell barrier reveals alterations induced by Plasmodium blood stage factors

TF Pais, C Penha-Gonçalves - Parasitology Research, 2023 - Springer
Cerebral malaria (CM) is a severe neurological condition caused by Plasmodium
falciparum. Disruption of the brain-blood barrier (BBB) is a key pathological event leading to …

Effect of caspase inhibitors on hemodynamics and inflammatory factors in ARDS model rats

A Liu, F Tian, Y Zhou, Z Pu - Scientific Reports, 2024 - nature.com
To study the effects of caspase inhibitors on hemodynamics and inflammatory factors in
acute respiratory distress syndrome (ARDS) model rats. Sixty healthy male Wistar rats were …