For decades, researches have concentrated on the mechanical properties, biodegradation,
and biocompatibility of implants used in the therapy of large size bone defect. In vivo studies …

Stem cells have been shown to play an important role in regenerative medicine due to their
proliferative and differentiation potential. The challenge, however, lies in regulating and …

The clinical utility of bone morphogenetic protein 2 (BMP2) is limited because of the poor
attraction between BMP2 and carriers, resulting in low loading efficiency and initial burst …

Constructing bionic extracellular matrix (ECM) is an attractive proposition for tissue
engineering and clinical regeneration therapy involving the stemness of stem cells. Here, a …

Investigation of phytochemicals and bioactive molecules is tremendously vital for the
applications of new plant resources in chemistry, food, and medicine. In this study, the …

Transcriptomic analysis revealed mesenchymal stem/stromal cells (MSCs) from various
origins exhibited distinct gene and protein expression profiles dictating their biological …

Purpose Puerarin (C21H20O10) is a phytoestrogen that possesses various pharmacological
effect, and several researches have revealed the relationship between puerarin and bone …

Peritendinous Adhesion is a complication after surgery for Achilles tendon injury. This
complication can be treated with surgical stents. Anti-adhesion membrane is an effective …

Extracellular matrix (ECM) is an intricate structure providing the microenvironment niche that
influences stem cell differentiation. This study aimed to investigate the efficacy of …

All cells possess an innate ability to respond to a range of mechanical stimuli through their
complex internal machinery. This comprises various mechanosensory elements that detect …