Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐
priority pathogens owing to their high association with mortalities and morbidities …

River ecosystems are very important parts of the water cycle and an excellent habitat, food,
and drinking water source for many organisms, including humans. Antibiotics are emerging …

Anaemia is a global public health concern, afflicting adolescent girls, women of reproductive
age, pregnant women and children in low-and middle-income countries. 1 Reduction of …

Background Most hospitals use traditional infection prevention (IP) methods for outbreak
detection. We developed the Enhanced Detection System for Healthcare-Associated …

Hospitals worldwide are facing an increasing incidence of hard-to-treat infections. Limiting
infections and providing patients with optimal drug regimens require timely strain …

Multidrug-resistant bacteria pose a serious health threat, especially in hospitals. Horizontal
gene transfer (HGT) of mobile genetic elements (MGEs) facilitates the spread of antibiotic …

Antimicrobial resistance (AMR) is a global public-health emergency, which threatens the
advances made by modern medical care over the past century. The World Health …

Even in the setting of optimal resuscitation in high-income countries severe sepsis and
septic shock have a mortality of 20–40%, with antibiotic resistance dramatically increasing …

Background Klebsiella pneumoniae is a leading cause of extended-spectrum β-lactamase
(ESBL)–producing hospital-associated infections, for which elderly patients are at increased …

Background Prospective whole-genome sequencing (WGS)-based surveillance may be the
optimal approach to rapidly identify transmission of multi-drug resistant (MDR) bacteria in …