Treating menopause—MHT and beyond

SR Davis, RJ Baber - Nature Reviews Endocrinology, 2022 - nature.com
Every woman who lives past midlife will experience menopause, which, by definition, is
complete cessation of ovarian function. This process might occur spontaneously (natural …

Sex differences in Alzheimer disease—the gateway to precision medicine

MT Ferretti, MF Iulita, E Cavedo, PA Chiesa… - Nature Reviews …, 2018 - nature.com
Alzheimer disease (AD) is characterized by wide heterogeneity in cognitive and behavioural
syndromes, risk factors and pathophysiological mechanisms. Addressing this phenotypic …

FSH blockade improves cognition in mice with Alzheimer's disease

J Xiong, SS Kang, Z Wang, X Liu, TC Kuo, F Korkmaz… - Nature, 2022 - nature.com
Alzheimer's disease has a higher incidence in older women, with a spike in cognitive
decline that tracks with visceral adiposity, dysregulated energy homeostasis and bone loss …

Premature ovarian insufficiency: an international menopause society white paper

N Panay, RA Anderson, RE Nappi, AJ Vincent… - …, 2020 - Taylor & Francis
The aim of this International Menopause Society White Paper on premature ovarian
insufficiency (POI) is to provide the latest information regarding this distressing condition …

Symptoms of menopause—global prevalence, physiology and implications

P Monteleone, G Mascagni, A Giannini… - Nature Reviews …, 2018 - nature.com
The symptoms of menopause can be distressing, particularly as they occur at a time when
women have important roles in society, within the family and at the workplace. Hormonal …

Understanding the impact of sex and gender in Alzheimer's disease: a call to action

RA Nebel, NT Aggarwal, LL Barnes, A Gallagher… - Alzheimer's & …, 2018 - Elsevier
Introduction Precision medicine methodologies and approaches have advanced our
understanding of the clinical presentation, development, progression, and management of …

2016 Alzheimer's disease facts and figures

Alzheimer's Association - Alzheimer's & Dementia, 2016 - Elsevier
This report describes the public health impact of Alzheimer's disease, including incidence
and prevalence, mortality rates, costs of care, and the overall impact on caregivers and …

Alzheimer's pathogenic mechanisms and underlying sex difference

D Zhu, A Montagne, Z Zhao - Cellular and Molecular Life Sciences, 2021 - Springer
AD is a neurodegenerative disease, and its frequency is often reported to be higher for
women than men: almost two-thirds of patients with AD are women. One prevailing view is …

Cardiovascular disease in women: clinical perspectives

M Garcia, SL Mulvagh, CN Bairey Merz… - Circulation …, 2016 - Am Heart Assoc
Cardiovascular disease continues to be the leading cause of death among women in the
United States, accounting for≈ 1 of every 3 female deaths. Sex-specific data focused on …

2016 IMS Recommendations on women's midlife health and menopause hormone therapy

RJ Baber, N Panay, A Fenton - Climacteric, 2016 - Taylor & Francis
Abstract The International Menopause Society (IMS) has produced these new 2016
recommendations on women's midlife health and menopause hormone therapy (MHT) to …