Bimetallic catalysis has emerged as an efficient strategy for the development of new
chemical reactions. Importantly, this strategy also provides a simple and powerful platform …

Dual catalysis is one of the most powerful strategies for the development of chemical
reactions in organic synthesis. This strategy can be divided into cooperative catalysis, relay …

Comprehensive computational studies were carried out to explore the mechanisms of
enantioselective Cu/Pd and stereodivergent Cu/Ir dual-catalytic syntheses of α, α …

Three-component carboacylation of simple alkenes with readily available reagents is
challenging. Transition metal-catalysed intermolecular carboacylation works for alkenes with …

The development of efficient and straightforward methods for obtaining all optically active
isomers of structurally rigid spirocycles from readily available starting materials is of great …

Spirooxindoles have emerged as promising architectures for engineering biologically active
compounds. The diastereodivergent construction of unique scaffolds of this type with full …

The stereodivergent total synthesis of all stereoisomers of bioactive natural compounds to
enable complete evaluation of stereochemical structure-activity relationships is highly …

Herein, we report a synthesis of cyclohexanones bearing multi‐continuous stereocenters by
combining copper‐catalyzed asymmetric conjugate addition of dialkylzinc reagents to cyclic …

Direct C–H alkylation of aldehydes represents a straightforward and step-economy strategy
for modular access to ketones. Herein, we report a direct C–H alkylation of aldehydes with …

Despite that asymmetric stereodivergent synthesis has experienced great success to
provide unusual processes for the creation of chirality complexity, concepts appliable to …