Machine learning for cardiovascular biomechanics modeling: challenges and beyond

A Arzani, JX Wang, MS Sacks, SC Shadden - Annals of Biomedical …, 2022 - Springer
Recent progress in machine learning (ML), together with advanced computational power,
have provided new research opportunities in cardiovascular modeling. While classifying …

MR Imaging of Human Brain Mechanics In Vivo: New Measurements to Facilitate the Development of Computational Models of Brain Injury

PV Bayly, A Alshareef, AK Knutsen, K Upadhyay… - Annals of biomedical …, 2021 - Springer
Computational models of the brain and its biomechanical response to skull accelerations
are important tools for understanding and predicting traumatic brain injuries (TBIs) …

Validation and comparison of instrumented mouthguards for measuring head kinematics and assessing brain deformation in football impacts

Y Liu, AG Domel, SA Yousefsani, J Kondic… - Annals of Biomedical …, 2020 - Springer
Because of the rigid coupling between the upper dentition and the skull, instrumented
mouthguards have been shown to be a viable way of measuring head impact kinematics for …

Development of a second-order system for rapid estimation of maximum brain strain

LF Gabler, JR Crandall, MB Panzer - Annals of biomedical engineering, 2019 - Springer
Diffuse brain injuries are assessed with deformation-based criteria that utilize metrics based
on rotational head kinematics to estimate brain injury severity. Although numerous metrics …

On-the-fly reduced order modeling of passive and reactive species via time-dependent manifolds

D Ramezanian, AG Nouri, H Babaee - Computer Methods in Applied …, 2021 - Elsevier
One of the principal barriers in developing accurate and tractable predictive models in
turbulent flows with a large number of species is to track every species by solving a separate …

The immune system's role in the consequences of mild traumatic brain injury (concussion)

LN Verboon, HC Patel, AD Greenhalgh - Frontiers in immunology, 2021 - frontiersin.org
Mild traumatic brain injury (mild TBI), often referred to as concussion, is the most common
form of TBI and affects millions of people each year. A history of mild TBI increases the risk of …

Neuro-ophthalmologic response to repetitive subconcussive head impacts: a randomized clinical trial

MK Nowak, ZW Bevilacqua, K Ejima… - JAMA …, 2020 - jamanetwork.com
Importance Subconcussive head impacts have emerged as a complex public health
concern. The oculomotor system is sensitive to brain trauma; however, neuro …

Hyper-acute effects of sub-concussive soccer headers on brain function and hemodynamics

C Grijalva, D Hale, L Wu, N Toosizadeh… - Frontiers in human …, 2023 - frontiersin.org
Introduction Sub-concussive head impacts in soccer are drawing increasing research
attention regarding their acute and long-term effects as players may experience thousands …

The relationship between brain injury criteria and brain strain across different types of head impacts can be different

X Zhan, Y Li, Y Liu, AG Domel… - Journal of the …, 2021 - royalsocietypublishing.org
Multiple brain injury criteria (BIC) are developed to quickly quantify brain injury risks after
head impacts. These BIC originated from different head impact types (eg sports and car …

Molecular imaging of neuroinflammation in patients after mild traumatic brain injury: a longitudinal 123I‐CLINDE single photon emission computed tomography study

SE Ebert, P Jensen, B Ozenne… - European Journal of …, 2019 - Wiley Online Library
Background and purpose Neuroinflammation has been proposed as part of the
pathogenesis of post‐concussion symptoms (PCS), but the inflammatory response of the …