Disintegration is the de-aggregation of particles within tablets upon exposure to aqueous
fluids. Being an essential step in the bioavailability cascade, disintegration is a fundamental …

Functional-related characteristics (FRCs) are properties of excipients that can potentially
influence one or more functions of that excipient in the final product. Knowledge of FRCs is …

Tablet disintegration is an important pre-requisite for drug dissolution and absorption. The
disintegration test is typically conducted at 37° C, but the intragastric temperature may vary …

Tablet disintegration is crucial for drug release and subsequent systemic absorption.
Although factors affecting the disintegrant's functionality have been extensively studied, the …

Alginates are biopolymers that have been investigated for their use in food and medical
fields. Minimal information is available regarding their potential application as tablet …

Nanocrystalline cellulose has achieved researchers' attention due to its exceptional physical
and biological characteristics, including its large surface area, biodegradability …

The influence of localization (intragranular, split or extragranular) of three superdisintegrants
(croscarmellose sodium, crospovidone, sodium starch glycolate) on granules and tablets …

The purpose of the study is to present the finite difference method (FDM) and demonstrate its
utility in modeling mass transport processes that are pharmaceutically relevant. In particular …

Microcrystalline cellulose (MCC) of different grades from different manufacturers differ in
particulate and powder properties significantly. The choice of MCC is important to the …

Stability studies are an integral part of the drug development process for any drug product. In
addition to monitoring chemical degradation, the physical stability of a drug product must …