Sepsis-associated acute kidney injury

CL Manrique-Caballero… - Critical Care …, 2021 - criticalcare.theclinics.com
Sepsis-associated acute kidney injury (S-AKI) is a common, life-threatening complication in
hospitalized and critically ill patients. S-AKI increases in-hospital mortality 6-fold to 8-fold, 1 …

[HTML][HTML] The definition of acute kidney injury and its use in practice

ME Thomas, C Blaine, A Dawnay, MAJ Devonald… - Kidney international, 2015 - Elsevier
Acute kidney injury (AKI) is a common syndrome that is independently associated with
increased mortality. A standardized definition is important to facilitate clinical care and …

The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer

S Chakraborty, S Kaur, S Guha, SK Batra - Biochimica et Biophysica Acta …, 2012 - Elsevier
Neutrophil gelatinase associated lipocalin (NGAL), also known as oncogene 24p3,
uterocalin, siderocalin or lipocalin 2, is a 24kDa secreted glycoprotein originally purified …

The outcome of neutrophil gelatinase-associated lipocalin-positive subclinical acute kidney injury: a multicenter pooled analysis of prospective studies

M Haase, P Devarajan, A Haase-Fielitz… - Journal of the American …, 2011 - jacc.org
Objectives: The aim of this study was to test the hypothesis that, without diagnostic changes
in serum creatinine, increased neutrophil gelatinase-associated lipocalin (NGAL) levels …

Urinary and serum biomarkers for the diagnosis of acute kidney injury: an in-depth review of the literature

J Vanmassenhove, R Vanholder… - Nephrology Dialysis …, 2013 - academic.oup.com
Background Acute kidney injury (AKI) remains associated with high morbidity and mortality,
despite progress in medical care. Although the RIFLE (Risk, Injury, Failure, Loss, End-Stage …

Neutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury: a critical evaluation of current status

A Haase-Fielitz, M Haase… - Annals of clinical …, 2014 - journals.sagepub.com
Background The early prediction of acute kidney injury (AKI) by current clinical and
laboratory methods remains inadequate. Neutrophil gelatinase-associated lipocalin (NGAL) …

The rise and fall of NGAL in acute kidney injury

J Mårtensson, R Bellomo - Blood purification, 2014 - karger.com
For many years, neutrophil gelatinase-associated lipocalin (NGAL) has been considered the
most promising biomarker of acute kidney injury (AKI). Commercial assays and point-of-care …

Biomarkers for prediction of renal replacement therapy in acute kidney injury: a systematic review and meta-analysis

SJ Klein, AK Brandtner, GF Lehner, H Ulmer… - Intensive care …, 2018 - Springer
Purpose Acute kidney injury (AKI) frequently occurs in critically ill patients and often
precipitates use of renal replacement therapy (RRT). However, the ideal circumstances for …

Biomarkers for the prediction of acute kidney injury: a narrative review on current status and future challenges

HRH De Geus, MG Betjes, J Bakker - Clinical kidney journal, 2012 - academic.oup.com
Acute kidney injury (AKI) is strongly associated with increased morbidity and mortality in
critically ill patients. Efforts to change its clinical course have failed because clinically …

Neutrophil gelatinase-associated lipocalin at ICU admission predicts for acute kidney injury in adult patients

HRH de Geus, J Bakker, EMEH Lesaffre… - American journal of …, 2011 - atsjournals.org
Rationale: Measured at intensive care unit admission (ICU), the predictive value of
neutrophil gelatinase-associated lipocalin (NGAL) for severe acute kidney injury (AKI) is …