Osteoarthritis (OA) is a chronic disease and the most common orthopedic disorder. A vast
majority of the social OA burden is related to hips and knees. The prevalence of knee OA …

Osteoarthritis (OA), a disabling joint inflammatory disease, is characterized by the
progressive destruction of cartilage, subchondral bone remodeling, and chronic synovitis …

The mechanism of the balance between subchondral angiogenesis and articular damage
within osteoarthritis (OA) progression remains a mystery. However, the lack of specific drugs …

While cartilage tissue engineering has significantly improved the speed and quality of
cartilage regeneration, the underlying metabolic mechanisms are complex, making research …

Osteoarthritis impairs the functions of various joints, such as knees, hips, hands and spine,
which causes pain, swelling, stiffness and reduced mobility in joints. Multiple factors …

Bionic mimics using natural cartilage matrix molecules can modulate the corresponding
metabolic activity by improving the microenvironment of chondrocytes. A bionic brush …

Background and objective With the development of global population aging, comorbidity (≥
2 diseases) is a common health problem among elderly people. Osteoarthritis (OA) and …

This study aimed to report the most current data on the incidence and disability-adjusted life
years (DALY) associated with osteoarthritis in China from 1990 to 2019. Publicly available …

Arthritis is a major cause of disability. Currently available anti-arthritic drugs, such as
disease-modifying anti-rheumatic drugs (DMARDs), have serious side-effects associated …

Background Articular injection of mesenchymal stem cells (MSCs) has been applied to treat
knee osteoarthritis (kOA), but its clinical outcomes are controversial. This study investigated …