Macrophages are present throughout the human body, constitute important immune effector
cells, and have variable roles in a great number of pathological, but also physiological …

Cellular reactive oxygen species (ROS) status is stabilized by a balance of ROS generation
and elimination called redox homeostasis. ROS is increased by activation of endoplasmic …

Inflammation is an essential immune response characterized by pain, swelling, redness,
heat, and impaired function. A controlled acute inflammatory response is necessary to fight …

Chronic oxidative stress and oxidative damage of the cerebral microvasculature and brain
cells has become one of the most convincing theories in neurodegenerative pathology …

Influenza A viral infections claim millions of lives worldwide and continue to impose a major
burden on healthcare systems. Current pharmacological strategies to control influenza A …

Significance: The evolution of the lungs and circulatory systems in vertebrates ensured the
availability of molecular oxygen (O2; dioxygen) for aerobic cellular metabolism of internal …

Senescent cells withdraw from the cell cycle and do not proliferate. The prevalence of
senescent compared to normally functioning parenchymal cells increases with age …

Xenogenic extracellular matrix (xECM)-based organ transplantation will be a promising
approach to address the problem of donor shortage for allotransplantation, which has …

Extreme heat stress-induced gastrointestinal injury and dysfunction may occur during
summer. We investigated possible mechanisms of heat stress-induced damage in the small …

Background and Purpose Haem oxygenase‐1 (HO‐1) is induced by thiazolidinediones
including rosiglitazone and exerts anti‐inflammatory effects in various models. However, the …