Fascin actin-bundling protein 1 in human cancer: promising biomarker or therapeutic target?
H Liu, Y Zhang, L Li, J Cao, Y Guo, Y Wu… - Molecular Therapy …, 2021 - cell.com
Fascin actin-bundling protein 1 (FSCN1) is a highly conserved actin-bundling protein that
cross links F-actin microfilaments into tight, parallel bundles. Elevated FSCN1 levels have …
cross links F-actin microfilaments into tight, parallel bundles. Elevated FSCN1 levels have …
Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis
Background Fascin-1 is an actin-bundling protein expressed in many human carcinomas,
although absent from most normal epithelia. Fascin-1 promotes filopodia formation …
although absent from most normal epithelia. Fascin-1 promotes filopodia formation …
Targeting YAP1/LINC00152/FSCN1 signaling axis prevents the progression of colorectal cancer
C Ou, Z Sun, X He, X Li, S Fan, X Zheng… - Advanced …, 2020 - Wiley Online Library
As a transcription coactivator, Yes‐associated protein 1 (YAP1)'s role in tumorigenesis is
well established. However, the mechanism of YAP1‐regulating long noncoding RNAs …
well established. However, the mechanism of YAP1‐regulating long noncoding RNAs …
miR-145-dependent targeting of junctional adhesion molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and …
Micro RNAs are small non-coding RNAs, which regulate fundamental cellular and
developmental processes at the transcriptional and translational level. In breast cancer, miR …
developmental processes at the transcriptional and translational level. In breast cancer, miR …
The endocrine disruptor bisphenol A (BPA) exerts a wide range of effects in carcinogenesis and response to therapy
SA Hafezi, WM Abdel-Rahman - Current molecular …, 2019 - ingentaconnect.com
Background: Bisphenol A (BPA) is a synthetic plasticizer that is commonly used in the
production of polycarbonate plastics and epoxy resins. Human exposure occurs when BPA …
production of polycarbonate plastics and epoxy resins. Human exposure occurs when BPA …
MicroRNA-451 regulates AMPK/mTORC1 signaling and fascin1 expression in HT-29 colorectal cancer
MB Chen, MX Wei, JY Han, XY Wu, C Li, J Wang… - Cellular signalling, 2014 - Elsevier
The earlier studies have shown that Fascin1 (FSCN1), the actin bundling protein, is over-
expressed in colorectal cancers, and is associated with cancer cell progression. Here, we …
expressed in colorectal cancers, and is associated with cancer cell progression. Here, we …
E-cadherin and the cytoskeletal network in colorectal cancer development and metastasis
A Buda, M Pignatelli - Cell communication & adhesion, 2011 - Taylor & Francis
Abnormalities in the expression and functional activity of cell adhesion molecules are
implicated in the development and progression of the majority of colorectal cancers (CRC) …
implicated in the development and progression of the majority of colorectal cancers (CRC) …
Human papillomaviruses and epstein–barr virus interactions in colorectal cancer: A brief review
Human papillomaviruses (HPVs) and the Epstein–Barr virus (EBV) are the most common
oncoviruses, contributing to approximately 10%–15% of all malignancies. Oncoproteins of …
oncoviruses, contributing to approximately 10%–15% of all malignancies. Oncoproteins of …
Emerging role of fascin-1 in the pathogenesis, diagnosis, and treatment of the gastrointestinal cancers
Simple Summary Gastrointestinal (GI) cancers, including esophageal, gastric, colorectal,
liver, and pancreatic cancers, remain as one of the leading causes of death worldwide, with …
liver, and pancreatic cancers, remain as one of the leading causes of death worldwide, with …
Expression profiling shows differential molecular pathways and provides potential new diagnostic biomarkers for colorectal serrated adenocarcinoma
P Conesa‐Zamora, J García‐Solano… - … journal of cancer, 2013 - Wiley Online Library
Serrated adenocarcinoma (SAC) is a recently recognized colorectal cancer (CRC) subtype
accounting for 7.5 to 8.7% of CRCs. It has been shown that SAC has a poorer prognosis and …
accounting for 7.5 to 8.7% of CRCs. It has been shown that SAC has a poorer prognosis and …